Surgical Site Infections after glioblastoma surgery: results of a multicentric retrospective study
- PDF / 693,214 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 118 Downloads / 204 Views
ORIGINAL PAPER
Surgical Site Infections after glioblastoma surgery: results of a multicentric retrospective study Henri Salle1,2 · Elise Deluche3 · Elodie Couvé‑Deacon4 · Anne‑Claire Beaujeux1 · Johan Pallud5,6 · Alexandre Roux5,6 · Arnaud Dagain7 · Amaury de Barros8 · Jimmy Voirin9,10 · Romuald Seizeur11,12 · Houda Belmabrouk11 · Leslie Lemnos1 · Evelyne Emery13,14 · Marie‑Jeanne Fotso15 · Julien Engelhardt16 · Vincent Jecko16,17 · Ilyess Zemmoura18,19 · Tuan Le Van20 · Moncef Berhouma21,22 · Hélène Cebula10 · Matthieu Peyre23,24 · Pierre‑Marie Preux25 · François Caire1,26 Received: 3 August 2020 / Accepted: 28 September 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Background The effects of surgical site infections (SSI) after glioblastoma surgery on patient outcomes are understudied. The aim of this retrospective multicenter study was to evaluate the impact of SSI on the survival of glioblastoma patients. Methods Data from SSI cases after glioblastoma surgeries between 2009 and 2016 were collected from 14 French neurosurgical centers. Collected data included patient demographics, previous medical history, risk factors, details of the surgical procedure, radiotherapy/chemotherapy, infection characteristics, and infection management. Similar data were collected from gender- and age-paired control individuals. Results We used the medical records of 77 SSI patients and 58 control individuals. 13 were excluded. Our analyses included data from 64 SSI cases and 58 non-infected glioblastoma patients. Infections occurred after surgery for primary tumors in 38 cases (group I) and after surgery for a recurrent tumor in 26 cases (group II). Median survival was 381, 633, and 547 days in patients of group I, group II, and the control group, respectively. Patients in group I had significantly shorter survival compared to the other two groups (p
Data Loading...
