Targeted Drug Delivery Methods and Protocols
This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies t
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Rachael W. Sirianni Bahareh Behkam Editors
Targeted Drug Delivery Methods and Protocols
Methods
in
M o l e c u l a r B i o lo g y
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Targeted Drug Delivery Methods and Protocols
Edited by
Rachael W. Sirianni Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Houston, TX, USA; Barrow Neurological Institute, Phoenix, AZ, USA
Bahareh Behkam Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA, USA; School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA, USA; Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, USA
Editors Rachael W. Sirianni Vivian L. Smith Department of Neurosurgery University of Texas Health Science Center at Houston Houston, TX, USA Barrow Neurological Institute Phoenix, AZ, USA
Bahareh Behkam Department of Mechanical Engineering Virginia Tech Blacksburg, VA, USA School of Biomedical Engineering and Sciences Virginia Tech Blacksburg, VA, USA Macromolecules Innovation Institute Virginia Tech Blacksburg, VA, USA
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-8659-0 ISBN 978-1-4939-8661-3 (eBook) https://doi.org/10.1007/978-1-4939-8661-3 Library of Congress Control Number: 2018948358 © Springer Science+Business Media, LLC, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana Press imprint is published by the registered company Springer Science+Business Media, LLC part of Springer Nature. The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.
Preface Our species has long recognized that where and how a drug is appli
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