The Burden of Chronic Heart Failure in Primary Care in Italy

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ORIGINAL ARTICLE

The Burden of Chronic Heart Failure in Primary Care in Italy Carlo Piccinni1,2 • Ippazio Cosimo Antonazzo1 • Monica Simonetti2 • Marco Giovanni Mennuni3 • Damiano Parretti4 • Claudio Cricelli4 • Delia Colombo5 • Mihaela Nica5 • Iacopo Cricelli2 • Francesco Lapi2

Received: 9 January 2017 / Accepted: 15 March 2017 Ó Springer International Publishing Switzerland 2017

Abstract Introduction Chronic heart failure (CHF) is a major public health concern. From a public health perspective, the epidemiology of CHF needs to be distinguished from that of its related acute form. Data stemming from primary care are crucial to better know and update the prevalence and incidence rates of CHF. Aim To update the epidemiology of CHF in an Italian primary care setting and to describe socio-demographic, lifestyle, and clinical characteristics of these patients. Methods A population-based study was conducted among 800 Italian general practitioners collecting data in a dedicated database. Information was extracted from adult subjects with a diagnosis of CHF from 2002 to 2013, and the prevalence and incidence rate of CHF were calculated. The study population was described in terms of socio-demographic, lifestyle, and clinical characteristics.

Results A total of 13,633 patients with CHF were identified. Overall, the prevalence of CHF was 1.25% (95% CI 1.23–1.27), and the incidence rate was 1.99 per 1000 person-years (95% CI 1.81–2.08). In this population, smoking, alcohol use, and obesity were present in 2.93, 0.45, and 10.80% of cases, respectively. Hypertension (58.40%), chronic kidney disease (51.36%), dyslipidaemia (44.62%), ischaemic heart disease (25.75%), and atrial fibrillation (25.32%) were the most represented comorbidities. Conclusion This study provides an updated epidemiological scenario of CHF in a primary care setting in Italy. These data may be useful to weight the social and economic impact of CHF and to plan strategies for improving the clinical care of CHF in general practice.

Electronic supplementary material The online version of this article (doi:10.1007/s40292-017-0193-4) contains supplementary material, which is available to authorized users.

1 Introduction

& Carlo Piccinni [email protected] 1

Pharmacology Unit, Department of Medical and Surgical Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy

2

Health Search, Italian College of General Practitioners and Primary Care, Florence, Italy

3

Cardiovascular Department, Humanitas Research Hospital, Rozzano, Milan, Italy

4

Italian College of General Practitioners and Primary Care, Florence, Italy

5

Patient Access Department, Novartis Farma, Origgio, Milan, Italy

Keywords Chronic heart failure  Epidemiology  Primary care  Italy

Heart failure (HF), which affects over 23 million people worldwide and causes nearly 300,000 deaths per year in the USA [1] and as many in Europe [2], represents a major public health issue. Overall, the estimated HF prevalence ranges from 1 to 3%, whereas the HF incidence rate ranges fro