The collection of five interesting cases of adrenal tumors from one medical center
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WORLD JOURNAL OF SURGICAL ONCOLOGY
CASE REPORT
Open Access
The collection of five interesting cases of adrenal tumors from one medical center Anna Babinska1*, Rafał Peksa2, Renata Swiątkowska-Stodulska1 and Krzysztof Sworczak1
Abstract Introduction: Adrenal tumors are detected incidentally in 4 to 8% of patients in imaging studies. Adenomas, pheochromocytomas and adrenocortical carcinomas represent the most common tumors of the adrenal glands. Rarely are final histopathological reports are surprising. Aim: The aim of our study is a retrospective analysis of selected clinical characteristics and hormonal studies in five cases of rare adrenal tumors. Materials and methods: We present five interesting cases of adrenal tumors: two medullary hyperplasia, one adenomatoid tumor, one hydatid cyst and a primary angiosarcoma of the adrenal gland. The final diagnosis was established by means of microscopic examination of the specimens. Conclusions: The number of adrenal tumors was increased due to widespread use of imaging procedures. In patients without any known extra-adrenal malignancy most lesions are benign, non-hyper functioning adenomas. Adrenal tumors should be evaluated biochemically and radiologically. Keywords: Medullary hyperplasia, Hydatid adrenal disease, Primary adrenal angiosarcoma, Adenomatoid tumor
Background Adrenal tumors are detected incidentally in approximately 4 to 8% of patients in imaging studies [1]. Adenomas, pheochromocytomas and adrenocortical carcinomas represent the most common tumors of the adrenal glands. Most of them are benign tumors but careful evaluation is required to rule out carcinoma and functional adenoma [1,2]. We present five very rare, interesting cases of adrenal tumors selected from the material of 1,248 patients from the Department of Endocrinology and Internal Diseases, Medical University of Gdansk, Poland. Case presentation Cases one and two: medullary hyperplasia – AMH (Adrenal medullary hyperplasia)
Two patients were admitted to our hospital in order to examine the cause of muscle weakness headaches, perspiration, palpitation and facial redness. A 46-year-old male presented with hypertension of 15-months duration (case * Correspondence: [email protected] 1 Department of Endocrinology and Internal Medicine, Medical University of Gdansk, Gdansk, Dębinki St 80-288, Poland Full list of author information is available at the end of the article
one). The patient’s family had no history of hypertension, cardiac arrhythmias or thyroid disorders. A 34-year-old female was referred for the evaluation of palpitation and facial redness of one-year’s duration (case two). The patient’s parents and sister had no history of hypertension or other endocrine disorders. On admission, there were no cushingoid signs. Paroxysmal hypertension had occurred, and was poorly controlled by antihypertensive drugs in both cases. Levels of urinary catecholamines were increased during the paroxysmal hypertension (see Table 1). Thyroid scans revealed normal-sized glands and their basic serum calcitonin lev
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