The correlation of retinol-binding protein-4 and lipoprotein combine index with the prevalence and diagnosis of acute co

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ORIGINAL ARTICLE

The correlation of retinol‑binding protein‑4 and lipoprotein combine index with the prevalence and diagnosis of acute coronary syndrome Yueqiao Si1 · Jingyi Liu1 · Chao Han1 · Ruijuan Wang1 · Tong Liu1 · Lixian Sun1  Received: 19 February 2020 / Accepted: 15 May 2020 © The Author(s) 2020

Abstract Retinol-binding protein-4 (RBP-4) along with the lipid profile plays crucial roles in Acute coronary syndrome (ACS). The study aimed to investigate the correlation of RBP-4, lipoprotein combine index (LCI), and RBP-4 + LCI with ACS. 163 ACS and 77 non-CAD in patients were consecutively enrolled in this study. The serum level of RBP-4 was measured via enzyme-linked immunosorbent assay. LCI was calculated using the formula: total cholesterol × triglyceride × low-density lipoprotein cholesterol/high-density lipoprotein cholesterol. RBP-4 ≥4 ng/ml, LCI ≥16 and LCI ≥16 + RBP-4 ≥4 ng/ml were new independent risk factors of ACS, and OR value of LCI ≥16 + RBP-4 ≥4 ng/ml was higher than that of RBP-4 and LCI combined (all p