The Kidney in Pregnancy
The behavior of the kidney in normal pregnancy, as well as in complicated pregnancy, is a very interesting, but still in many ways an unknown topic in renal medicine. It is undoubtedly difficult to determine, even in normal women, the behavior of renal he
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TOPICS IN RENAL MEDICINE Vittorio E. Andreucci, Series Editor
THE KIDNEY IN PREGNANCY
EDITED BY VITTORIO E. ANDREUCCI
MARTINUS NIJHOFF PUBLISHING A MEMBER OF THE KLUWER ACADEMIC PUBLISHERS GROUP BOSTON
DORDRECHT
LANCASTER
Copyright 1986 © by Martinus Nijholf Publishing, Boston Softcover reprint of the hardcover 1st edition 1986 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanical, photocopying, recording, or otherwise, without written permission of the publisher, Martinus Nijholf Publishing, 190 Old Derby Street, Hingham, Massachusetts 02043. Distributors
for the United States and Canada: Kluwer Academic Publishers, 190 Old Derby Street, Hingham, MA, 02043, USA for the UK and Ireland: Kluwer Academic Publishers, MTP Press Limited, Falcon House, Queen Square, Lancaster LAl 1RN, UK for all other countries: Kluwer Academic Publishers Group, Distribution Centre, P.O. Box 322, 3300 AH Dordrecht, The Netherlands
Library of Congress Cataloging in Publication Data Main entry under title: The Kidney in pregnancy. (Topics in renal medicine) 1. Pregnancy, Complications of. 2. KidneysDiseases. I. Andreucci, Vittorio E. I. Series. [DNLM: 1. Kidney-physiology. 2. Kidney-physiopathology. 3. Pregnancy Complications. WJ 301 K46] RG580.K5K523 1985 618.3 85-11437 ISBN-13 : 978-1-4612-9638-6 001: 10.1007/978-1-4613-2619-9
e-ISBN-13 : 978-1-4613-2619-9
To my mother, wife, and daughter and to all pregnant and nonpregnant women
CONTENTS
Contributing Authors IX List of Abbreviations xv Preface XVll 1. Renal hemodynamics in pregnancy
1
ANTONIO DAL CANTON, VITTORIO E. ANDREUCCI
2. Pathogenesis of preeclampsia
13
GINA GREGORINI, NORBERTO PERICO, GIUSEPPE REMUZZI
3. Coagulation and pregnancy
35
EDOARDO ROSSI, MARIA MATILDE COSSU, PIERO CAPETTA
4. Pathology of the kidney in preeclampsia
47
JAMES R. TAYLOR, BENJAMIN H. SPARGO
5. Renal function during normal pregnancy and the effect of renal disease and preeclampsia 65 JOHN M. DAVISON
6. Sodium metabolism in normal pregnancy and in preeclampsia
81
WOLFRAM E. NOLTEN, EDWARD N. EHRLICH
7. Hypertension complicating pregnancy
95
NORMAN F. GANT, JACK A. PRITCHARD
8. Treatment of chronic hypertension in pregnancy
123
VITTORIO E. ANDREUCCI, ANTONIO DAL CANTON, DOMENICO RUSSO
vii
viii
Contents
9. Proteinuria during pregnancy
133
PRISCILLA S. KINCAID-SMITH, ROBYN A. NORTH, GAVIN J. BECKER, KENNETH F. FAIRLEY
10. Acute renal failure in pregnancy
165
..
NATHALIE PERTUISET, DOMINIQUE GANEVAL, JEAN-PIERRE GRUNFELD
11. Successful pregnancies in women on regular dialysis treatment and women with a functioning transplant 185 SABRI CHALLAH, ANTONY J. WING, MICHEL BROYER, GIANFRANCO RIZZONI
12. Pregnancy following renal transplantation ISRAEL PENN
13. Urinary tract infection in pregnancy lAIN R. MCFADYEN
Index
231
205
195
Contributing Authors
Vittorio E. Andreucci, MD Professor of Nephrology and Chairman, Department of Nephrology Second Faculty of Medicine