The severity of symptoms is insufficient to predict major alterations to quality of life of patients with fecal incontin
- PDF / 448,668 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 8 Downloads / 169 Views
ORIGINAL ARTICLE
The severity of symptoms is insufficient to predict major alterations to quality of life of patients with fecal incontinence or chronic constipation Dann Joseph Ouizeman 1 & Eugenia Marine-Barjoan 2 & Audrey Hastier-De Chelles 1 & Marie De Matharel 1 & Marie-Lise Montoya 1 & Rodolphe Anty 1,3,4 & Thierry Piche 1,3 Accepted: 30 June 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose Evaluate the impact of fecal incontinence (FI) and chronic constipation (CC) on the quality of life (QoL) in a large population and determine if a threshold of symptom scores was associated with alterations to QoL. Methods A total of 422 outpatients with FI (n = 186), CC (n = 186), and mixed FI-CC (n = 50) referred for anorectal manometry were included prospectively. All patients completed a set of questionnaires to evaluate the severity of FI and CC (respectively Jorge and Wexner and KESS scores) and their impact on QoL (Gastrointestinal Quality of Life Index (GIQLI)). Results The study population included 81.8% women. The QoL was altered to the same degree for both FI and CC, with significant more marked impairments in patients with mixed FI-CC (median GIQLI: 91 (71–108) vs. 91 (73–108) vs. 81 (57– 97) respectively, p = 0.05). The symptom severity significantly but weekly correlated with the GIQLI score (r2 = − 0.454 for FI and r2 = − 0.483 for CC, p < 0.001). Thus, the large dispersion of the data flawed the identification of a threshold for symptom severity that could predict major impairment to QoL. Conclusion The QoL was equally altered for FI and CC. Although the symptom score severity was slightly but significantly associated with alterations to QoL, it was not possible to determine a threshold for symptom scores that predict an alteration to QoL. Therefore, the evaluation of QoL in parallel to the assessment of the symptom score is required to endorse the entire spectrum of the severity of CC or FI. Keywords Fecal incontinence . Chronic constipation . Quality of life . Sexual involvement
Introduction Fecal incontinence (FI) and chronic constipation (CC) are highly prevalent diseases in the general population [1, 2] and are associated with major alterations to the quality of life [3–8]. It is controversial as to whether clinical factors
* Dann Joseph Ouizeman [email protected] 1
Digestive Center, University Hospital of Nice, 151 route de Saint Antoine de Ginestière - CS 23079, 06202 Nice Cedex, France
2
Public Health Department, University Hospital of Nice, Nice, France
3
Faculty of Medicine, University of Nice – Côte d’Azur, Nice, France
4
U1065, C3M, Team 8, Chronic Liver Diseases Associated with Obesity and Alcohol, National Institute of Health and Medical Research (INSERM), Nice, France
of FI and CC can help predict alterations to quality of life. In some studies, the frequency, amount, and urgency of defecation have been identified as good predictors of the quality of life of patients with FI [8, 9]. Moreover, factors associated with an impaired quality of lif
Data Loading...
