Three-dimensional Dixon fat-water separated breath-held imaging of myocardial delayed enhancement
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BioMed Central
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Poster presentation
Three-dimensional Dixon fat-water separated breath-held imaging of myocardial delayed enhancement Manojkumar Saranathan*1 and James F Glockner2 Address: 1GE Healthcare, Rochester, MN, USA and 2Mayo Clinic, Rochester, MN, USA * Corresponding author
from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. 21-24 January 2010 Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P102
doi:10.1186/1532-429X-12-S1-P102
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-infoThis abstract is available from: http://jcmr-online.com/content/12/S1/P102 © 2010 Saranathan and Glockner; licensee BioMed Central Ltd.
Introduction Myocardial delayed enhancement (MDE) imaging of infarction is commonly performed using an inversion-recovery (IR) two-dimensional (2D) breath-held fast gradient recalled echo (FGRE) pulse sequence. Three-dimensional (3D) imaging can improve scanning efficiency by acquiring the desired volume in a single breath-hold. Fat suppression could greatly improve visualization of epicardial enhancement (which occurs in transmural myocardial infarction and myocarditis) as well as pericardial enhancement.
Purpose
parallel imaging scheme with acceleration factor of 2.5 in the phase encoding direction yielded an overall breathholding time of 22-25 s. A robust region-growing based phase-corrected 2-point Dixon reconstruction algorithm of Ma et al. was used. Patients with known or suspected myocardial infarction, myocarditis, pericarditis, or nonischemic cardiomyopathy were imaged after informed consent on a 1.5 T GE SIGNA scanner using an 8-channel phased array coil. Imaging was performed approximately 10-15 minutes after bolus injection of 0.2 mmol/kg of Gadolinium DTPA contrast agent. The 3D Dixon FGRE scan immediately followed the IR prepared 2D FGRE acquisition.
To investigate a novel Dixon fat-water separated 3D breath-hold technique for fat suppressed imaging of MDE.
Methods An ECG-gated dual-echo bipolar-readout 3DFGRE pulse sequence was developed. High receiver bandwidths enabled placement of opposed- and in-phase echoes at 2.4/ 4.8 ms, achieving compact TRs. Elimination of explicit fat suppression enabled use of a novel k-space segmentation scheme that is efficient and has desirable motion insensitivity properties. Radial fanbeam k-space segmentation of an elliptical ky-kz region (corners skipped) was employed for efficient coverage of k-space, enabling 3D data acquisition in a single breath-hold. Within each fanbeam, kspace points were acquired in the order of increasing kr. In each R-R interval, a non-selective 180° pulse followed by an inversion time (TI) delay of 200-250 ms preceded data acquisition at ~300 ms (32-36 points). A self-calibrated
in Short transmural Figure patient axis 1 with 2D delayed MDE inferior/inferoseptal enhancemen
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