Titanium dioxide nanoparticles promote arrhythmias via a direct interaction with rat cardiac tissue
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Savi et al. Particle and Fibre Toxicology (2014) 11:63 DOI 10.1186/s12989-014-0063-3
RESEARCH
Open Access
Titanium dioxide nanoparticles promote arrhythmias via a direct interaction with rat cardiac tissue Monia Savi1,3†, Stefano Rossi1,3†, Leonardo Bocchi1†, Laura Gennaccaro1, Francesca Cacciani1, Alessio Perotti1, Davide Amidani1, Rossella Alinovi2,3, Matteo Goldoni2,3, Irene Aliatis4, Pier Paolo Lottici4, Danilo Bersani4, Marco Campanini5, Silvana Pinelli2,3, Marta Petyx6, Caterina Frati2, Andrea Gervasi7, Konrad Urbanek8, Federico Quaini2, Annamaria Buschini1, Donatella Stilli1, Claudio Rivetti1, Emilio Macchi1,3, Antonio Mutti2,3, Michele Miragoli3,9* and Massimiliano Zaniboni1,3*
Abstract Background: In light of recent developments in nanotechnologies, interest is growing to better comprehend the interaction of nanoparticles with body tissues, in particular within the cardiovascular system. Attention has recently focused on the link between environmental pollution and cardiovascular diseases. Nanoparticles
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