Radiopharmaceuticals A Guide to PET/CT and PET/MRI
This book provides a rapid and concise guide to PET (PET/CT and PET/MRI) molecular imaging, concentrating extensive information on PET radiopharmaceuticals in a single volume.The book reflects the rapid development of several PET tracers over the last dec
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Radiopharmaceuticals
Ferdinando Calabria • Orazio Schillaci Editors
Radiopharmaceuticals A Guide to PET/CT and PET/MRI Second Edition
Editors Ferdinando Calabria Department of Nuclear Medicine and Theranostics Mariano Santo Hospital Cosenza Italy
Orazio Schillaci Department of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy
© Servizi Scientifici 2017 First Edition © Springer Nature Switzerland AG 2020 Second Edition ISBN 978-3-030-27778-9 ISBN 978-3-030-27779-6 (eBook) https://doi.org/10.1007/978-3-030-27779-6 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To Nicoletta, Maria Beatrice and Agnese Felicia. O.S. To my father, my principal sponsor. F.C.
Preface
Two years have elapsed since the publication of the book Radiopharma ceuticals, a well-received volume reflecting the state of the art in hybrid PET/CT and PET/MR imaging with novel radiopharmaceuticals. Since its publication, the necessity to cover a larger spectrum of PET tracers has emerged, allowing physicians, residents, and students to deepen their knowledge about PET molecular imaging in a single volume. Therefore, this edition is enriched by two new chapters, respectively, that focus on prostate cancer imaging with 68Ga-PSMA and imaging of tau pathology. Previous chapters are also updated by new interesting clinical cases and novel applications. The panorama of PET molecular imaging has been improved in the last decades by the development of several novel radiopharmaceuticals; some of them play an established role while other tracers are showing interesting preliminary results. In this scenario, the most useful PET tracer, the 18F-FDG, shows a limi
