Radix Angelicae dahuricae Baizhi
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Chinese Pharmacopoeia X Pharmacopoeia of the People’s Republic of China, English Edition 1997/2005(1)
Official drugs:(1)
Angelica dahurica (Fisch. Ex Hoffm.) Benth. et Hook f. Angelica dahurica (Fisch. Ex Hoffm.) Benth. et Hook f. var. formosana (Boiss.) Shan et Yuan – Apiaceae – The drug is known as Xiang Bai Zhi, Byakushi (Japanese), Paegchi (Korean) and Chinese Angelica Root (English).
Description of the drug:(1,4)
Long-conical, 10–25 cm long, 1.5–2.5 cm in diameter. Externally greyish-brown or yellowish-brown, the root stock obtusely quadrangular or subrounded, with longitudinal wrinkles, rootlet scars and lenticel-like transverse protrudings, some of them arranged in four longitudinal rows. Apex with dented stem scars. Texture compact, fracture white or greyish-white and starchy, cambium ring brown, subsquare or subrounded, scattered with many brown oil dots in bark. Odour aromatic; taste pungent and bitter.
Pretreatment of the raw drug (1) Eliminate foreign matter, grade according to size, soak briefly, cut into thick slices and dry.
Medicinal use(1,2,3,4)
In Traditional Chinese Medicine the decoction is used as an antipyretic and analgesic for patterns of externally contracted windcold, especially those with headache; it is also used for supraorbital pain, nasal congestion, and toothache. Externally it reduces swelling and expels pus in early stages of surface sores and carbuncles. The drug expels dampness and alleviates discharge, in particular vaginal discharge.
H. Wagner et al. (eds.), Chromatographic Fingerprint Analysis of Herbal Medicines © Springer-Verlag/Wien 2011
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Radix Angelicae dahuricae – Baizhi
Effects and indications according to Traditional Chinese Medicine(1,2,3,4) Taste:
acrid
Temperature:
warm
Channels entered:
lung, stomach
Effects:
dispels wind, removes damp, clears blocked noses, relieves pain and promotes subsidence of swelling and drainage of pus.
Symptoms and indications:
headache, particularly pain in the forehead, and blocked nose due to colds; sinusitis; toothache; excessive leukorrhea; swelling, painfull sores and wounds.
Main constituents (see Fig. 1)(5–20) – furanocoumarins: e.g. imperatorin, isoimperatorin, phellopterin, bergapten, cnidilin(6–10) – coumarins: e.g. scopoletin, 7-demethylsuberosin, cedrelopsin(6–8) – coumarin glycosides: e.g. nodakenin, 3Ê-hydroxymarmesinin(11) – polyacetylenes: falcarindiol(12) – steroles: stigmasterol, sitosterol, – lactones: β-angelica lactone, 2-hydroxy-3,4-dimethyl-2-butene-4-olide, γ-nonalactone and γ-decalactone(13–15) – unsaturated fatty acids(12)
Fig. 1: Formulae of the main constituents 172
Radix Angelicae dahuricae – Baizhi Pharmacology:(12, 21–37) – Antimicrobial activity: in vitro inhibitory activity against Shigella and Salmonella species, Bacillus subtilis, Escherichia coli, Cladosporium herbarum and Aspergillus candidus (phellopterin, byak angelicin, scopoletin, heraclenol). – Effective in promotion of healing and avoiding sequelae of corneal ulcers secondary flash burns. – A powder composed of Angelicae d
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