Re-irradiation: New Frontiers

New developments such as refined combined modality approaches and significant technical advances in radiation treatment planning and delivery are facilitating the re-irradiation of previously exposed volumes. As a consequence, both palliative and curative

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Series Editors Albert L. Baert Luther W. Brady Hans-Peter Heilmann Hedvig Hricak Michael Knauth Michael Molls Carsten Nieder Maximilian F. Reiser Luther W. Brady Hans-Peter Heilmann Michael Molls Carsten Nieder

For further volumes: http://www.springer.com/series/174

Carsten Nieder • Johannes A. Langendijk Editors

Re-Irradiation: New Frontiers

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Editors Carsten Nieder Department of Internal Medicine Radiation Oncology Unit Nordlandssykehuset HF 8092 Bodoe Norway e-mail: [email protected]

Johannes A. Langendijk Department of Radiation Oncology University Medical Center Groningen Hanzeplein 1, P.O. Box 30.001 9700 RB Groningen The Netherlands e-mail: [email protected]

ISSN 0942-5373 ISBN 978-3-642-12467-9 e-ISBN 978-3-642-12468-6 DOI 10.1007/978-3-642-12468-6 Springer Heidelberg Dordrecht London New York Ó Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudio Calamar, Berlin/Figueres Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

One of the most difficult problems facing oncologists is the patient who has been clinically treated by radiation therapy and presents with no evidence of systemic disease but with persistent local disease in the original volume irradiated. In the past, most oncologists would find this an insurmountable problem with which to deal. However, with the development of new technologies including Intensity Modulated Radiation Therapy, Image Guided Radiation Therapy, Tomotherapy, Stereotactic Body Radiosurgical Techniques and Proton Beams opens entirely new vistas as to how best to handle these problems. Along with these technical developments has been a better understanding of altered fractionation technologies and how they might be used in developing a treatment program to previously irradiated volumes. In the evolution of events, it is important to recognize that two significant situations present in this matter. One is the patient w

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