Recurrent bladder cystitis: who takes the role?

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TOPIC PAPER

Recurrent bladder cystitis: who takes the role? Mustafa Soytas1   · Cagri Kactan1   · Selcuk Guven1  Received: 19 December 2019 / Accepted: 30 March 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  In this review, we discuss how the approach should be throughout the symptomatic and diagnostic process of recurrent bladder cystitis. Methods and results  The available literature regarding recurrent bladder cystitis in the PubMed database has been reviewed. While urinary tract infections (UTIs) are amongst the most commonly seen diseases in society, the probability of having a UTI in women within a year is 15%. Within a lifetime, it is above 50%. In addition to the related comorbidities and decreased quality of life, the resulting cost constitutes a serious burden on national economies. Recurrent UTI (rUTI) refers to a group of patients who have suffered from a UTI at least three times in the last 12 months or at least two times during the previous 6 months and have diminished quality of life. During this chronic and bothersome process, it is also complicated as to who is going to make the diagnosis of patients and by whom treatment or follow-up will be provided. Conclusion  Although there is no clear answer to this issue in the literature, the urologist might be the moderator of this chronic process as the physician who most frequently faces this condition in daily practice, is most aware of the uroanatomy as well as the pathophysiology and performs relevant operations in cases of necessity. At this point, rather than limiting the evaluation and treatment to a single specialty, it is crucial to solve the problem by using a multidisciplinary approach. Keywords  Management · Multidisciplinary approach · Prevention · Recurrent urinary tract infection · Recurrent UTI · Women

Introduction In healthy women, the most common cause of antibiotic use is uncomplicated urinary tract infection. Antibiotic resistance among uropathogens has increased dramatically within last 25 years. Overuse of antibiotics has led to the emergence of drug-resistant organisms and multidrug resistance. Overall lifetime prevalence of UTI in women is over 50% and annual costs in the US alone are over $ 2.6 billion in 2010 data [1, 3]. Approximately 45–50% of women suffer from a UTI at least once in their lifetime, and 20–30% of these patients experience UTI recurrence within 3–4 months of * Cagri Kactan [email protected] Mustafa Soytas [email protected] Selcuk Guven [email protected] 1



the initial infection [2, 3]. Recurrent UTI defines the patient cohort who have developed UTI at least three times within last 12 months or at least two times within last 6 months and have decreased quality of life. In regards to recurrent UTI, another defining classification is the concept of ‘Index Patient’. It describe that who refers to a female patient, with no immunosuppression, anatomical anomaly or multi-drug resistant bacteria suffering from an uncomplicated rUTI [4, 5]. Although antibacteri