Regulation of Angiogenesis
- PDF / 60,809,503 Bytes
- 437 Pages / 481.89 x 691.654 pts Page_size
- 3 Downloads / 213 Views
Regulation of Angiogenesis Edited by 1. D. Goldberg E.M. Rosen
Birkhauser Verlag Basel· Boston· Berlin
Editors
Itzhak D. Goldberg, M. D. Eliot M. Rosen, M. D. Ph. D. Department of Radiation Oncology Long Island Jewish Medical Center 270-05 76th Avenue New Hyde Park, New York, NY 11042 USA
A CIP catalogue record for this book is available from the Library of Congress, Washington, D.C., USA. Deutsche Bibliothek Cataloging-in-Publication Data
EXS. - Basel; Boston; Berlin: Birkhauser. Friiher Schriftenreihe Fortlaufende Bei!. zu: Experientia Regulation of angiogenesis / ed. by 1. D. Goldberg; E. M. Rosen. - Basel; Boston; Berlin: Birkhauser, 1997 (EXS; 79) ISBN -13: 978-3-0348-9864·5 e-ISBN -13: 978-3-0348 -9006-9 Dor: 10.1007/978-3-0348 -9006-9 NE: Goldberg, ItzhakD. [Hrsg.] The publisher and editors cannot assume any legal responsibility for information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks, etc. in this publication, even if not identified as such, does not imply that they are exempt from the relevant protective laws and regulations or free for general use. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright holder must be obtained. © 1997 Birkhauser Verlag, P.O. Box 133, CH-40 10 Basel, Switzerland Softcover reprint of the hardcover 1st edition 1997 Printed on acid-free paper produced from chlorine-free pulp. TCF 00 ISBN -13: 978-3-0348-9864-5 987654321
Dedicated to the memory of my beloved father Aryeh Goldberg a man of uncompromising integrity and valor, whose love and guidance I will always cherish. Itzhak D. Goldberg
Contents Introduction
IX
I. D. Goldberg and E.M. Rosen
J. Folkman Angiogenesis and angiogenesis inhibition: An overview
Significance of angiogenesis in human disease P J. Polverini Role of the macrophage in angiogenesis-dependent diseases
11
J. P. Johnson and J. N Bruce
Angiogenesis in human gliomas: Prognostic and therapeutic implications . . . . . . . . . . . . . . . . . . . . . . . . . .
29
C. Guerin and J. Laterra Regulation of angiogenesis in malignant gliomas
47
M. H Witte, D. L. Way, C. L. Witte and M. Bernas Lymphangiogenesis: Mechanisms, significance and clinical implications . . . . . . . . . . . . . . . . . . . . . . . . . .
65
K. Engels, S. B. Fox and A. L. Harris Angiogenesis as a biologic and prognostic indicator in human breast carCInoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
113
Molecular mechanisms of angiogenesis regulation Control of angiogenesis by cytokines and growth factors S. Klein, M. Roghani and D. B. Rifkin Fibroblast growth factors as angiogenesis factors: New insights in
