Relationships among pulmonary capillary wedge pressure, dry weight and natriuretic peptide in patients undergoing hemodi
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ORIGINAL INVESTIGATION
Relationships among pulmonary capillary wedge pressure, dry weight and natriuretic peptide in patients undergoing hemodialysis: a three‑dimensional speckle tracking echocardiography study Hidemaro Sato1 · Masanori Kawasaki2 · Ryuhei Tanaka3 · Takashi Yoshizane4 · Koji Ono4 · Mitsunobu Tadokoro1 · Yoko Yano1 · Takehito Kondou1 · Tatsuya Kariya1 · Kijun Nagata1 · Koshi Gotoh1 · Shigeki Sawada1 · Toshiyuki Noda4 · Sachiro Watanabe4 Received: 2 October 2019 / Revised: 15 December 2019 / Accepted: 9 January 2020 © Japanese Society of Echocardiography 2020
Abstract Background Although the evaluation of fluid status in hemodialysis (HD) patients is useful, relationship among pulmonary capillary wedge pressure (PCWP), dry body weight (DW) and natriuretic peptide has not been elucidated. In addition, there has been no objective marker for instantaneously monitoring hemodynamic improvement in response to HD. We previously reported that PCWP and time constant of left ventricular pressure decline (Tau) can be noninvasively estimated (ePCWP and eTau) by speckle tracking echocardiography (STE). The aim of this study was to elucidate the relationship among ePCWP, eTau, DW and natriuretic peptide in patients undergoing HD. Methods We measured ePCWP and body weight (BW) by STE in 81 patients and ANP and BNP by blood examination in 31 patients just before and after HD during sinus rhythm. Results The ePCWP decreased after HD, and this was associated with reductions in ln ANP, eTau and BW (r = 0.523, 0.271 and 0.814, respectively, p
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