Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia
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Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: A six-country study Károly R Kulich*1, Ahmed Madisch2, Franco Pacini3, Jose M Piqué4, Jaroslaw Regula5, Christo J Van Rensburg6, László Újszászy7, Jonas Carlsson1, Katarina Halling1 and Ingela K Wiklund1 Address: 1AstraZeneca R&D, Medical Science, Mölndal, S-431 86, Sweden, 2Medical Department I, Technical University Hospital, Dresden, 01307, Germany, 3Azienda Ospedaliera Careggi, U. O. di Gastroenterologia ed Endoscopia digestiva, Villa Medicea, Viale Pieraccini, 17, 50139, Firenze, Italy, 4Servicio de Gastroenterología, Hospital Clinic de Barcelona, Villarroel 170, 08036, Spain, 5Klinika Gastroenterologii CMKP, Centrum Onkologii, Roentgen Street 5, 02-781, Warszawa, Poland, 6Gastroenterology Unit, Tygerberg Hospital, Cape Town, 7505, South Africa and 7Semmelweis Hospital, Internal Medicine, Csabai Kapu 9-11, 3501, Miskolc, Hungary Email: Károly R Kulich* - [email protected]; Ahmed Madisch - [email protected]; Franco Pacini - [email protected]; Jose M Piqué - [email protected]; Jaroslaw Regula - [email protected]; Christo J Van Rensburg - [email protected]; László Újszászy - [email protected]; Jonas Carlsson - [email protected]; Katarina Halling - [email protected]; Ingela K Wiklund - [email protected] * Corresponding author
Published: 31 January 2008 Health and Quality of Life Outcomes 2008, 6:12
doi:10.1186/1477-7525-6-12
Received: 21 August 2007 Accepted: 31 January 2008
This article is available from: http://www.hqlo.com/content/6/1/12 © 2008 Kulich et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Symptoms of dyspepsia significantly disrupt patients' lives and reliable methods of assessing symptom status are important for patient management. The aim of the current study was to document the psychometric characteristics of the Gastrointestinal Symptom Rating Scale (GSRS) and the Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD) in Afrikaans, German, Hungarian, Italian, Polish and Spanish patients with dyspepsia. Methods: 853 patients with symptoms of dyspepsia completed the GSRS, the QOLRAD, the 36item Short-Form Health Survey (SF-36) and the Hospital Anxiety and Depression scale. Results: The internal consistency reliability of the GSRS was 0.43–0.87 and of the QOLRAD 0.79– 0.95. Test-retest reliability of the GSRS was 0.36–0.75 and of the QOLRAD 0.41–0.82. GSRS Abdominal pain domain correlated significantly with all QOLRAD domains in most language versions, and with SF-36 Bodily pain in all versions. QOLRAD domains correlated significantly
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