Reproducibility of global LV function and dyssynchrony parameters derived from phase analysis of gated myocardial perfus
- PDF / 954,043 Bytes
- 10 Pages / 593.972 x 792 pts Page_size
- 20 Downloads / 147 Views
b c d e f g h i j k l
m
´ i, Rio Nuclear Medicine Department, Hospital Universitario Antonio Pedro-EBSERH-UFF, Nitero de Janeiro, Brazil Nuclear Medicine Department, Institute of Cardiology, La Habana, Cuba Nuclear Medicine, Spedali Civili, Brescia, Italy All India Institute of Medical Sciences, New Delhi, India Hospital Clinico Universidad de Chile, Santiago, Chile Fundacion Valle del Lili, Cali, Colombia Hospital Juan Ramon Jimenez, Huelva, Spain Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, DF, Mexico Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan Dr. B L Kapur Memorial Hospital, New Delhi, India Fundacion Cardioinfantil, Bogota, Colombia Nuclear Medicine and Diagnostic Imaging Section, International Atomic Energy Agency, Vienna, Austria Emory University, Atlanta, GA
Received Jun 29, 2020; Revised Aug 14, 2020; accepted Sep 4, 2020 doi:10.1007/s12350-020-02397-6
Background. Gated myocardial perfusion scintigraphy (GMPS) phase analysis is an important tool to investigate the physiology of left ventricular (LV) dyssynchrony. We aimed to test the performance of GMPS LV function and phase analysis in different clinical settings and on a diverse population.
The authors of this article have provided a PowerPoint file, available for download at SpringerLink, which summarises the contents of the paper and is free for re-use at meetings and presentations. Search for the article DOI on SpringerLink.com. Electronic supplementary material The online version of this article (https://doi.org/10.1007/s12350-020-02397-6) contains supplementary material, which is available to authorized users.
Reprint requests: Fernando de Amorim Fernandes, MSc, Nuclear Medicine Department, Hospital Universitario Antonio PedroEBSERH-UFF, 303 Marqueˆs de Parana street, Nitero´i, Rio de Janeiro 24033-900, Brazil; [email protected] 1071-3581/$34.00 Copyright Ó 2020 American Society of Nuclear Cardiology.
Amorim Fernandes et al Reproducibility of of myocardial perfusion SPECT
Journal of Nuclear CardiologyÒ
Methods. This is a post hoc analysis of a prospective, non-randomized, multinational, multicenter cohort study. Clinical evaluation and GMPS prior to cardiac resynchronization therapy (CRT)(baseline) and 6-month post CRT (follow-up) were done. LV end-systolic volume (LVESV), LV end-diastolic volume (LVEDV), LV ejection fraction (LVEF), LV phase standard deviation (LVPSD), and percentage of left ventricle non-viable (PLVNV) were obtained by 10 centers and compared to the core lab. Results. 276 GMPS studies had all data available from individual sites and from core lab. There were no statistically significant differences between all variables except for LVPSD. When subjects with no mechanical dyssynchrony were excluded, LVPSD difference became non-significant. LVESV, LVEF, LVPSD and PLVNV had strong correlation in site against core lab comparison. Bland–Altman plots demonstrated good agreement. Conclusions. The presented correlation and agreement of LV function and dyssynchrony analysis over differe
Data Loading...
