Residual renal function and nutrition in young patients on chronic hemodialysis

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ORIGINAL ARTICLE

Residual renal function and nutrition in young patients on chronic hemodialysis Isabella Guzzo & Elvira Mancini & Séverin Kengne Wafo & Lucilla Ravà & Stefano Picca

Received: 30 August 2008 / Revised: 29 January 2009 / Accepted: 3 February 2009 / Published online: 7 March 2009 # IPNA 2009

Abstract Residual renal function (RRF) has been associated with a better nutritional status in adult patients on chronic dialysis, but there is as yet no data available for young patients on chronic hemodialysis (HD). We have retrospectively analyzed 3-day dietary reports and simultaneous urea kinetic monitoring data (n=179) of 30 children, adolescents and young adults on chronic HD. The protein catabolic rate (PCR) was calculated and normalized by body weight (nPCR). The HD dialysis dose (Kt/VHD), RRF (calculated by urea clearance, Ku, and expressed as residual Kt/V) and total Kt/V (Kt/Vtot) were evaluated. In all patients, nPCR was correlated with dietary protein intake (nDPI) (p< 0.0001) and Kt/Vtot (p