Retinal Degenerative Diseases Mechanisms and Experimental Therapy

The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium will

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John D. Ash · Robert E. Anderson  Matthew M. LaVail  Catherine Bowes Rickman  Joe G. Hollyfield · Christian Grimm Editors

Retinal Degenerative Diseases Mechanisms and Experimental Therapy

Advances in Experimental Medicine and Biology Series Editor: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S.Kline Institute for Psychiatric Rrch, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Tehran, Iran

More information about this series at http://www.springer.com/series/5584

John D. Ash  •  Robert E. Anderson Matthew M. LaVail  •  Catherine Bowes Rickman Joe G. Hollyfield  •  Christian Grimm Editors

Retinal Degenerative Diseases Mechanisms and Experimental Therapy

Editors John D. Ash Department of Ophthalmology University of Florida Gainesville, FL, USA Matthew M. LaVail School of Medicine Beckman Vision Center University of California San Francisco San Francisco, CA, USA Joe G. Hollyfield Division of Ophthalmology Case Western Reserve University Cleveland, OH, USA

Robert E. Anderson Ophthalmology and Cell Biology University of Oklahoma Health Sciences Center Oklahoma City, OK, USA Catherine Bowes Rickman Departments of Ophthalmology and Cell Biology Duke Eye Center, Duke University Medical Center Durham, NC, USA Christian Grimm Department of Ophthalmology University Hospital Zurich Zurich, Switzerland

ISSN 0065-2598     ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-319-75401-7    ISBN 978-3-319-75402-4 (eBook) https://doi.org/10.1007/978-3-319-75402-4 Library of Congress Control Number: 2018936145 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This S