RETRACTED ARTICLE: The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imagi
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Egyptian Journal of Radiology and Nuclear Medicine
RESEARCH
Open Access
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Mohamed Ali EL-Adalany, Amany Ezzat Mohamed Mousa and Dina EL-Metwally*
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The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors Abstract
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Background: MRI is considered to be the imaging modality of choice in preoperative diagnosis of parotid gland tumors and differentiating benign from malignant ones. Recently, functional MR imaging sequences including dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) and diffusion-weighted imaging (DWI) have significantly contributed to the diagnosis of head and neck masses. The purpose of this study was to evaluate the diagnostic value of combined DCE-MRI and DWI in characterization of parotid gland tumors. Results: There was significant difference between benign and malignant parotid gland tumors as regard the type of time intensity curve (TIC) (P < 0.001). There was significant difference between pleomorphic adenoma (PMA) and malignant parotid gland tumors (MT) as regard mean ADC value (P = 0.046) and TTP (P = 0.002). There was no significant difference between Warthin’s tumor (WT) and malignant parotid gland tumors as regard the ADC value and TTP (P > 0.5); on the other hand, WT usually have high WR when compared with MT (P = 0.004). Combined use of DCE-MRI and DWI had 100% sensitivity, 90.5% specificity, and 93.3% accuracy in differentiating benign from malignant parotid gland tumors.
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Conclusion: Combined use of DCE-MRI and DWI could result in high sensitivity, specificity, and diagnostic accuracy in characterization of parotid gland tumors.
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Keywords: Parotid gland, MRI, DWI, DCE-MRI
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Background Salivary gland tumors (SGTs) account for nearly 3% of tumors that occur in the maxillofacial region; about 80% of all SGTs are found in the parotid gland with an incidence of malignancy within the parotid gland tumors about 20%. Proper preoperative diagnosis of these tumors is essential for adequate surgical planning [1]. Clinical assessment has a limited role in diagnosing malignant parotid tumors. In addition, fine needle aspiration biopsy (FNAB) is sometimes inconclusive and insufficient [2]. * Correspondence: [email protected] Department of Diagnostic Radiology, Faculty of Medicine, Mansoura university, Mansoura, Egypt
Several imaging modalities such as ultrasonography and computed tomography (CT) may aid in diagnosis of parotid gland tumors, but now magnetic resonance imaging (MRI) is considered to be the imaging modality of choice in preoperative diagnosis of parotid gland tumors and differentiating benign from malignant ones [1]. MRI gives information on the exact location, extent of the lesion, relation to the surroundings structures, and allows assessment of perineural spread and bone invasion. However, it was reported that both benign and malignant parotid gland tumors show considerable overlap with regard to imaging appearance such as tumor ma
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