Reviews of Physiology, Biochemistry and Pharmacology, Vol. 165

T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as "Sweet Spots" for Targeted Therapies. D.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle

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Reviews of Physiology, Biochemistry and Pharmacology

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Bernd Nilius  Susan G. Amara  Thomas Gudermann  Reinhard Jahn  Roland Lill  Stefan Offermanns  Ole H. Petersen Editors

Reviews of Physiology, Biochemistry and Pharmacology 165

Editors Bernd Nilius KU Leuven Dept. of Cell. and Molecular Medicine Laboratory of Ion Channel Research Herestraat 49 Campus Gasthuisberg O&N B-3000 Leuven Belgium Thomas Gudermann Ludwig-Maximilians-Universita¨t Mu¨nchen Medizinische Fakulta¨t Walther-Straub-Institut fu¨r Pharmakologie Mu¨nchen Germany Roland Lill University of Marburg Inst. Zytobiologie und Zytopathologie Marburg Germany

Susan G. Amara University of Pittsburgh School of Medicine Department of Neurobiology Biomedical Science Tower 3 Pittsburgh, PA USA Reinhard Jahn Max-Planck-Institute for Biophysical Chemistry Go¨ttingen Germany Stefan Offermanns Max-Planck-Institut fu¨r Herz und Lungen Abteilung II Bad Nauheim Germany

Ole H. Petersen School of Biosciences Cardiff University Museum Avenue Cardiff, UK ISSN 0303-4240 ISSN 1617-5786 (electronic) ISBN 978-3-319-00998-8 ISBN 978-3-319-00999-5 (eBook) DOI 10.1007/978-3-319-00999-5 Springer Cham Heidelberg New York Dordrecht London Library of Congress Control Number: 2013950276 # Springer International Publishing Switzerland 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the m