Right ventricular diastolic function in aging: a head-to-head comparison between phase-contrast MRI and Doppler echocard

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ORIGINAL PAPER

Right ventricular diastolic function in aging: a head‑to‑head comparison between phase‑contrast MRI and Doppler echocardiography Nadjia Kachenoura1 · Emilie Bollache1 · Gilles Soulat2,3 · Stéphanie Clément‑Guinaudeau3 · Golmehr Ashrafpoor1,3 · Ludivine Perdrix3 · Benoit Diebold1,2 · Magalie Ladouceur2,3 · Elie Mousseaux2,3 Received: 19 May 2020 / Accepted: 18 September 2020 © Springer Nature B.V. 2020

Abstract To evaluate right ventricle (RV) diastolic function from phase-contrast MRI (PC-MRI) in aging. 89 healthy individuals (50 men, 43 ± 15 years) underwent cardiac MRI including 2D PC-MRI (1.5T) and reference Doppler echocardiography of both ventricles on the same day. Conventional echocardiographic parameters were estimated: early (E, cm/s) and atrial (A) peak velocities as well as myocardial early peak longitudinal velocity (E′). PC-MRI images were analyzed using custom software, providing: E′, E and A waves along with respective peak flow rates (Ef, Af, mL/s) and filling volume (mL), for both ventricles. Intra- and inter-observer reproducibility was studied in 30 subjects and coefficients of variation (CoV) as well as intra-class correlation coefficients (ICC) were provided. RV diastolic function indices derived from PC-MRI data were reproducible (CoV ≤ 21%, ICC ≥ 0.75) and reliable as reflected by significant associations with left ventricular diastolic function indices assessed using both echocardiography (linear regression Pearson correlation coefficient r ≤ 0.59) and PC-MRI (r ≤ 71). Despite the fair associations between RV echocardiography and PC-MRI (r ≤ 0.25), the highest correlation with age was obtained for MRI Ef/Af ratio (r = − 0.64, p 

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