Salivary Gland Cancer From Diagnosis to Tailored Treatment

This clinically oriented book provides a comprehensive update on the biology, diagnosis, and treatment of salivary gland cancer. Detailed information is presented on molecular characterization and radiological staging, and a series of treatment-related ch

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Salivary Gland Cancer

Lisa Licitra  •  Laura D. Locati Editors

Salivary Gland Cancer From Diagnosis to Tailored Treatment

Editors Lisa Licitra Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori Milan Milan Italy

Laura D. Locati Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori Milan Milan Italy

ISBN 978-3-030-02957-9    ISBN 978-3-030-02958-6 (eBook) https://doi.org/10.1007/978-3-030-02958-6 Library of Congress Control Number: 2018965730 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

1 Management-Based Pathology Assessment of Salivary Gland Carcinomas ������������������������������������������������������������������������������������   1 Adel K. El-Naggar 2 Molecular Characterization of Salivary Gland Carcinomas ����������������  17 André Fehr, Jörn Bullerdiek, Thorsten Jaekel, and Thomas Löning 3 The Role of Imaging in Staging and Follow-Up of Salivary Gland Tumors��������������������������������������������������������������������������������������������  33 Silvana Sdao, Enrico Civelli, Alessandra Alessi, and Giuseppina Calareso 4 Surgery for Malignant Parotid Gland Tumours ������������������������������������  45 Vincent Vander Poorten 5 Surgery for Parapharyngeal Tumors ������������������������������������������������������  69 Orlando Guntinas-Lichius 6 Surgery for Submandibular and Sublingual Malignant Tumors����������  85 Natalie L. Silver and Randal S. Weber 7 Surgery for Malignant Tumors of the Minor Salivary Glands���������������� 97 Davide Lombardi, Remo Accorona, Davide Lancini, Vittorio Rampinelli, Anna Bozzola, and Piero Nicolai 8