Sertraline
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Reversible cerebral vasoconstriction syndrome: case report A 42-year-old woman developed reversible cerebral vasoconstriction syndrome (RCVS) during treatment with sertraline [duration of treatment to reaction onset and outcome not stated]. The woman had history of sertraline use [route, dosage and indication not stated]. She presented to a neurology department in hospital with a thunderclap headache. Five days later, she started showing low level of awareness, loss of ambulation and incoherent speech. CT scan and MRI showed multiple strokes located in arterial watershed and a cortical surface nonaneurysmal subarachnoid haemorrhage. The cerebral angiography revealed multiple segments of narrowing in vessel caliber. Two probable diagnoses of vasculitis of the central nervous system and RCVS were considered. The cerebrospinal fluid findings were normal. After 3 months, the follow up angiography demonstrated a normal vessel caliber. The woman’s clinical outcome was poor and follow-up revealed spastic tetraplegia and mutism. The follow-up MRI revealed a larger infarcts, especially in the territory of both anterior cerebral arteries. Therefore, he was considered to have RCVS with poor prognosis. Manez M, et al. Reversible cerebral vasoconstriction syndrome: A dramatic case report. European Journal of Neurology 27 (Suppl. 1): 1051 (plus poster) abstr. EPO3054, 803498998 May 2020. Available from: URL: http://doi.org/10.1111/ene.14305 [abstract]
0114-9954/20/1819-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 29 Aug 2020 No. 1819
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