Signaling-Mediated Control of Cell Division From Oogenesis to Oocyt
This volume covers the current knowledge base on the role of signaling and environmental pathways that control the normal development of germline stem cells, meiotic progression of oocytes, events of oocyte maturation and fertilization, and the birth of a
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Swathi Arur Editor
SignalingMediated Control of Cell Division From Oogenesis to Oocyte-to-Embryo Development
Results and Problems in Cell Differentiation
Volume 59
Series editors Jacek Z. Kubiak, Rennes CX, France Malgorzata Kloc, Houston, TX, USA
More information about this series at http://www.springer.com/series/400
Swathi Arur Editor
Signaling-Mediated Control of Cell Division From Oogenesis to Oocyte-to-Embryo Development
Editor Swathi Arur Dept. of Genetics, Genes & Dev. Program UT MD Anderson Cancer Center Houston, Texas USA
ISSN 0080-1844 ISSN 1861-0412 (electronic) Results and Problems in Cell Differentiation ISBN 978-3-319-44819-0 ISBN 978-3-319-44820-6 (eBook) DOI 10.1007/978-3-319-44820-6 Library of Congress Control Number: 2016961937 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Germ cells sustain life through generations. Germ cells are set aside from somatic cells in the embryo and go through the specialized cell division process of meiosis to produce the gametes—the oocyte or the sperm. The process whereby germ cells develop into gametes is governed via several developmental, nutritional, and other environmental cues or signals. Unsurprisingly, due to a variety of causes, sometimes these signals are spatially and/or temporally anomalous during organismal development, and such anomalies can manifest as birth defects in the progeny. Thus, elucidating how a multitude of molecular mediators integrate the various developmental and environmental signals to coordinate germ cell formation, maintenance, and function remains an active area of investigation. In both invertebrate and vertebrate animals, environmentally activated signaling pathways regulate production of gamete
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