Silica-Induced Immunotoxicity: Chronic and Aberrant Activation of Immune Cells

Occupational and chronic exposure to silica particles causes pulmonary fibrosis known as silicosis, which is a typical form of pneumoconiosis. Although the respiratory complications of silicosis include pulmonary tuberculosis, pleurisy, bronchitis, and ot

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Takemi Otsuki Claudia Petrarca Mario Di Gioacchino Editors

Allergy and Immunotoxicology in Occupational Health

Current Topics in Environmental Health and Preventive Medicine Series editor T. Otsuki Kurashiki, Japan

Current Topics in Environmental Health and Preventive Medicine, published in partnership with the Japanese Society of Hygiene, is designed to deliver well written volumes authored by experts from around the globe, covering the prevention and environmental health related to medical, biological, molecular biological, genetic, physical, psychosocial, chemical, and other environmental factors. The series will be a valuable resource to both new and established researchers, as well as students who are seeking comprehensive information on environmental health and health promotion.

More information about this series at http://www.springer.com/series/13556

Takemi Otsuki • Claudia Petrarca Mario Di Gioacchino Editors

Allergy and Immunotoxicology in Occupational Health

Editors Takemi Otsuki Department of Hygiene Kawasaki Medical School Kurashiki, Japan Mario Di Gioacchino Immuntotoxicology and Allergy Unit & Occupational Biorepository, Center of Excellence on Aging and Translational Medicine (CeSI-MeT) “G. D’Annunzio” University Foundation Chieti, Italy

Claudia Petrarca Immuntotoxicology and Allergy Unit & Occupational Biorepository, Center of Excellence on Aging and Translational Medicine (CeSI-MeT) “G. D’Annunzio” University Foundation Chieti, Italy

Department of Medicine and Science of Aging

G. d’Annunzio University Chieti, Italy

ISSN 2364-8333 ISSN 2364-8341 (electronic) Current Topics in Environmental Health and Preventive Medicine ISBN 978-981-10-0349-3 ISBN 978-981-10-0351-6 (eBook) DOI 10.1007/978-981-10-0351-6 Library of Congress Control Number: 2016953187 © Springer Science+Business Media Singapore 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered compa