Single breath-hold whole heart coronary MRA with isotropic spatial resolution using highly-accelerated parallel imaging
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BioMed Central
Open Access
Poster presentation
Single breath-hold whole heart coronary MRA with isotropic spatial resolution using highly-accelerated parallel imaging with a 32-element coil array Jian Xu*1, Daniel Kim2, Ricardo Otazo2, Benjamin Ge3, Sven Zuehlsdorff4, Xiaoming Bi4, Bernd Stoeckel5 and Daniel Sodickson2 Address: 1Siemens Medical Solutions USA Inc. and PolyTechnic Institute of NYU, New York, NY, USA, 2Radiology, New York University, NY, USA, 3Medical School, New York University, NY, USA, 4Siemens Medical Solutions USA Inc., Chicago, IL, USA and 5Siemens Medical Solutions USA Inc., New York, NY, USA * Corresponding author
from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. 21-24 January 2010 Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P47
doi:10.1186/1532-429X-12-S1-P47
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-infoThis abstract is available from: http://jcmr-online.com/content/12/S1/P47 © 2010 Xu et al; licensee BioMed Central Ltd.
Introduction
Methods
Whole heart coronary MRA (CMRA) is typically performed with navigator gating because of the extensive data acquisition needed to achieve an isotropic spatial resolution on the order of 1-2 mm3 with full anatomic coverage (10-16 cm). Previous studies have shown that whole heart CMRA can be performed with either a single [1] or double [2,3] breath-hold (BH) approach using highlyaccelerated parallel imaging. The single breath-hold approach [1] acquires the coil sensitivity data immediately before and after the coronary MRA data within the same cardiac cycle, whereas the double BH approach acquires coil sensitivity data in a separate BH. The single BH approach lengthens the time between the T2 and fat suppression pulses to the image acquisition, and the double BH approach may suffer from misregistration. We propose to acquire the coil sensitivity and coronary MRA data in two separate cardiac phases (early systole and mid diastole, respectively) both within a single BH, in order to circumvent the aforementioned problems.
Experimental studies were performed in 2 healthy volunteers on a 1.5 T scanner (Siemens;Avanto). The relevant steady state free precession (TrueFisp) pulse sequence parameters are: FOV 360 × 360 × 102 mm3, Matrix 224 × 224 × 64, slice thickness 1.6 mm, the voxel size is 1.6 × 1.6 × 1.6 mm3, interpolated to 0.8 × 0.8 × 0.8 mm3, acceleration-factor 4 × 2 (4 in PE and 2 in PA direction), segment 42, TR 3 ms, TE 1.4 ms, partial Fourier in both PE and PA directions (6/8), slice oversampling-rate 12.5%, T2 and fat-suppression preparation pulses were used. Image reconstruction was performed using the 2D GRAPPA technique. Using identical parameters, we compared two cases: 1) double BH approach and 2) single BH approach where the coil sensitivity and image data are acquired at early systole and mid di
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