Strain analysis using feature tracking cardiac magnetic resonance (FT-CMR) in the assessment of myocardial viability in

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ORIGINAL PAPER

Strain analysis using feature tracking cardiac magnetic resonance (FT‑CMR) in the assessment of myocardial viability in chronic ischemic patients Sara W. Tantawy1,2   · Shaimaa Abdelsattar Mohammad1   · Ahmed M. Osman1   · Wesam El Mozy2,3   · Ahmed S. Ibrahim1  Received: 29 May 2020 / Accepted: 4 September 2020 © Springer Nature B.V. 2020

Abstract The purpose of this study is to test the capability of a commercially available feature tracking-cardiac magnetic resonance (FT-CMR) strain analysis software module in differentiating between viable and non-viable myocardium in chronic ischemic patients. Thirty chronic ischemic patients and 10 healthy volunteers were enrolled. Cine images were used for peak circumferential and radial strains quantification using dedicated FT-CMR software. Global strain was compared between patients and controls. In patients, segmental strain was compared in viable and non-viable myocardium determined by late gadolinium enhancement (LGE); and in segments with wall abnormalities. Among 480 myocardial segments analyzed in patients, 76 segments were non-viable on LGE. The mean left ventricular ejection fraction (LVEF) of the patients (87% males, mean age 55 ± 12 years) was 40 ± 12% vs. 61 ± 5% for the controls (80% males, mean age 39 ± 11 years). Peak global circumferential strain (GCS) and global radial strain (GRS) were significantly impaired in patients compared to controls (−13.89 ± 4.12% vs. −19.84 ± 1.47%), p