Synthetic Biology A Sociology of Changing Practices

This book explores the emergence of a new scientific field, synthetic biology, and the many bold promises its proponents have made to change the future of science, industry, humanity and the global environment. It explores how people, including academics,

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Synthetic Biology A Sociology of Changing Practices Andrew S. Balmer University of Manchester, UK

Katie Bulpin University of Manchester, UK

and

Susan Molyneux-Hodgson University of Sheffield, UK

SYNTHETIC BIOLOGY: A SOCIOLOGY OF CHANGING PRACTICES

Copyright © Andrew S. Balmer, Katie Bulpin and Susan Molyneux-Hodgson 2016. All rights reserved. No reproduction, copy or transmission of this publication may be made without written permission. No portion of this publication may be reproduced, copied or transmitted save with written permission. In accordance with the provisions of the Copyright, Designs and Patents Act 1988, or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, Saffron House, 6–10 Kirby Street, London EC1N 8TS. Any person who does any unauthorized act in relation to this publication may be liable to criminal prosecution and civil claims for damages. First published 2016 by PALGRAVE MACMILLAN The authors have asserted their rights to be identified as the authors of this work in accordance with the Copyright, Designs and Patents Act 1988. Palgrave Macmillan in the UK is an imprint of Macmillan Publishers Limited, registered in England, company number 785998, of Houndmills, Basingstoke, Hampshire, RG21 6XS. Palgrave Macmillan in the US is a division of Nature America, Inc., One New York Plaza, Suite 4500 New York, NY 10004–1562. Palgrave Macmillan is the global academic imprint of the above companies and has companies and representatives throughout the world. E-PDF ISBN: 978-1-137-49542-6 ISBN: 978-1-137-49541-9 DOI: 10.1057/9781137495426 Distribution in the UK, Europe and the rest of the world is by Palgrave Macmillan®, a division of Macmillan Publishers Limited, registered in England, company number 785998, of Houndmills, Basingstoke, Hampshire RG21 6XS. Library of Congress Cataloging-in-Publication Data is available from the Library of Congress A catalog record for this book is available from the Library of Congress Library of Congress Cataloging-in-Publication Data Balmer, Andrew S., 1983– Synthetic biology : a sociology of changing practices / Andrew S. Balmer, University of Manchester, UK, Katie Bulpin, University of Sheffield, UK, Susan Molyneux-Hodgson, University of Sheffield, UK. pages cm Includes bibliographical references and index. 1. Synthetic biology. 2. Bioengineering. I. Bulpin, Katie, 1982– II. Molyneux-Hodgson, Susan. III. Title. TA164.B35 2016 660.6—dc23

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Contents

Acknowledgements

vi

List of Abbreviations

vii

1

Synthetic Biology in Situ

1

Coda 1

Towards Collaborative Practices

33

2

Barriers

41

Coda 2

Brokering Relations

72

3

Bacteria

80

Coda 3

Critics on the Inside

108

4

Bodies

116

Coda 4

Reciprocal Reflexivity

143

5

Enacting Ontologies, Failure and Time

151

Coda 5

Reflections on Collaboration

181

References

191

Index

203

v

Acknowledgements First, we must thank our colleagues and collaborators with whom we worked during our investigations into