Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors
This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussion
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Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors
Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors
Dustin L. Williams Editor
Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors
Editor Dustin L. Williams Department of Veterans Affairs Salt Lake City, UT, USA Department of Orthopaedics University of Utah Salt Lake City, UT, USA Department of Pathology University of Utah Salt Lake City, UT, USA Department of Bioengineering University of Utah Salt Lake City, UT, USA Department of Physical Medicine and Rehabilitation Uniformed Services University of the Health Sciences Bethesda, MD, USA
ISBN 978-3-030-30666-3 ISBN 978-3-030-30667-0 (eBook) https://doi.org/10.1007/978-3-030-30667-0 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To those who suffer from infection, biofilm- related, or otherwise. Don’t lose hope. Solutions are on the horizon as thousands of researchers and clinicians work to resolve infectious problems. Healing will one day transcend pain. And to my wife, who has never let me quit. She’s consistently been there with her hands on my back, when my shoulders have needed squaring and I’ve had to face the wind.
Foreword
For decades, bacterial and polymicrobial biofilms have been recognized as unique microbial communities, distinct from their planktonic or single sessile microbe relatives. Biofilm phenotypes, behaviors, properties, and persistence survival strategies are now known to be responsible for diverse scientific, medical, and technological problems. Despite substantial published scientific evidence elucidating thei
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