Th 17 Cells: Role in Inflammation and Autoimmune Disease
With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mech
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Series Editor Prof. Michael J. Parnham PhD Director of Preclinical Discovery Centre of Excellence in Macrolide Drug Discovery GlaxoSmithKline Research Centre Zagreb Ltd. Prilaz baruna Filipovic´a 29 HR-10000 Zagreb Croatia Advisory Board G. Z. Feuerstein (Wyeth Research, Collegeville, PA, USA) M. Pairet (Boehringer Ingelheim Pharma KG, Biberach a. d. Riss, Germany) W. van Eden (Universiteit Utrecht, Utrecht, The Netherlands)
Forthcoming titles: New Therapeutic Targets in Rheumatoid Arthritis, P.-P. Tak (Editor), 2009 Inflammatory Cardiomyopathy (DCM) – Pathogenesis and Therapy, H.-P. Schultheiß, M. Noutsias (Editors), 2009 Occupational Asthma, T. Sigsgaard, D. Heederick (Editors), 2009 Nuclear Receptors and Inflammation, G.Z. Feuerstein, L.P. Freedman, C.K. Glass (Editors), 2009 (Already published titles see last page.)
Th 17 Cells: Role in Inflammation and Autoimmune Disease
Valérie Quesniaux Bernhard Ryffel Franco Di Padova Editors
Birkhäuser Basel · Boston · Berlin
Editors Valérie Quesniaux University of Orléans and CNRS UMR6218 Molecular Immunology and Embryology 45071 Orléans France
Bernhard Ryffel University of Orléans and CNRS UMR6218 Molecular Immunology and Embryology 45071 Orléans France
Franco Di Padova Novartis Institutes for Biomedical Research NIBR WSJ 386-906 4002 Basel Switzerland
Library of Congress Control Number: 2008935061
Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the internet at http://dnb.ddb.de
ISBN 978-3-7643-8680-1 Birkhäuser Verlag AG, Basel – Boston – Berlin The publisher and editor can give no guarantee for the information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks etc. in this publication, even if not identified as such, does not imply that they are exempt from the relevant protective laws and regulations or free for general use. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright owner must be obtained. © 2009 Birkhäuser Verlag AG Basel · Boston · Berlin P.O. Box 133, CH-4010 Basel, Switzerland Part of Springer Science+Business Media Printed on acid-free paper produced from chlorine-free pulp. TCF c Cover design: Markus Etterich, Basel Cover illustration: IL-17 positive cells in rheumatoid synovium. With friendly permission of Pierre Miossec, University of Lyon. Printed in Germany ISBN 978-3-7643-8680-1 e-ISBN 978-3-7643-8681-8 987654321 www.birkhauser.ch
Contents
List of contributors
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