THE ARTERIAL CHEMORECEPTORS

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan

Recent Volumes in this Series Volume 572 RETINAL DEGENERATIVE DISEASES Edited by Joe Hollyfield, Robert Anderson, and Matthew LaVail Volume 573 EARLY LIFE ORIGINS OF HEALTH AND DISEASE Edited by Marelyn Wintour-Coghlan and Julie Owens Volume 574 LIVER AND PANCREATIC DISEASES MANAGEMENT Edited by Nagy A. Habib and Ruben Canelo Volume 575 DIPEPTIDYL AMINOPEPTIDASES: BASIC SCIENCE AND CLINICAL APPLICATIONS Edited by Uwe Lendeckel, Ute Bank, and Dirk Reinhold Volume 576 N-ACETYLASPARTATE: A UNIQUE NEURONAL MOLECULE IN THE CENTRAL NERVOUS SYSTEM Edited by John R. Moffett, Suzannah B. Tieman, Daniel R. Weinberger, Joseph T. Coyle and Aryan M.A. Namboodiri Volume 577 EARLY LIFE ORIGINS OF HEALTH AND DISEASE Edited by E. Marelyn Wintour and Julie A. Owens Volume 578 OXYGEN TRANSPORT TO TISSUE XXVII Edited by Giuseppe Cicco, Duane Bruley, Marco Ferrari, and David K. Harrison Volume 579 IMMUNE MECHANISMS IN INFLAMMATORY BOWEL DISEASE Edited by Richard S. Blumberg Volume 580 THE ARTERIAL CHEMORECEPTORS Edited by Yoshiaki Hayashida, Constancio Gonzalez, and Hisatake Kondo A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

THE ARTERIAL CHEMORECEPTORS Edited by

Yoshiaki Hayashida International Buddhist University, Osaka, Japan

Constancio Gonzalez University of Valladolid, Valladolid, Spain and

Hisatake Kondo Tohoku University, Sendai, Japan

ISBN-10 ISBN-13 ISBN-10 ISBN-13

0-387-31310-9 (HB) 978-0-387-31310-8 (HB) 0-387-31311-7 (e-book) 978-0-387-31311-5 (e-book)

© 2006 Springer All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science + Business Media, Inc., 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed in the Netherlands. 9 8 7 6 5 4 3 2 1 springer.com

Contents Preface ............................................................................................... xiii A Tribute to Professor Autar Singh Paintal................................................1 Ravi K. and Vijayan V.K.

Structure of Chemoreceptors Immunolocalization of