The Burden of Rotavirus Acute Gastroenteritis in Europe
Rotavirus (RV) is the leading cause of severe gastroenteritis in children under 5 years of age. In this chapter we will document the burden of rotavirus gastroenteritis in the 27 countries of the European Union.
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Introduction: Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1234
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Rotavirus Disease Burden in Europe: the Available Data . . . . . . . . . . . . . . . . . . . . . . . 1235 Symptomatic Cases Not Requiring Professional Medical Care . . . . . . . . . . . . . . . . . . . . . 1235 Ambulatory Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1235 Emergency Department Visits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1236 Hospitalizations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1236 Nosocomial Infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1236 Deaths . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1237
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Considerations Regarding Interpretation and Comparison of Reported Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1237 3.1 Seasonality . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1239 3.2 Age . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1239 3.3 Case Definitions and Study Methodology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1239 Summary Points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1240
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Springer Science+Business Media LLC 2010 (USA)
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The Burden of Rotavirus Acute Gastroenteritis in Europe
Abstract: > Rotavirus (RV) is the leading cause of severe > gastroenteritis in children under 5 years of age. In this chapter we will document the burden of > rotavirus gastroenteritis in the 27 countries of the European Union. Data on rotavirus disease burden is lacking for about half of the countries of the European Union. The available data for the other half show differences that do not necessarily reflect country-specific differences, but that may also be due to differences in study characteristics and quality. Based on the available literature, the annual > incidence of RV disease in the European Union ranges from 0.06–4.15% of the children aged ambulatory care, 0–2.65% of the children aged International Classification of Disease, ninth edition; NRV, nosocomial rotavirus infection; O, outpatient visit; P, pediatrician; PROTECT, Pediatric ROTavirus European CommiTee; RV, rotavirus; RVGE, rotavirus gas
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