The coronavirus diseases 2019 (COVID-19) pneumonia with spontaneous pneumothorax: a case report

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The coronavirus diseases 2019 (COVID-19) pneumonia with spontaneous pneumothorax: a case report Xiaoxing Chen1†, Guqin Zhang2†, Yueting Tang3, Zhiyong Peng4 and Huaqin Pan4*

Abstract Background: The outbreak of the novel coronavirus (COVID-19) that was firstly reported in Wuhan, China, with cases now confirmed in more than 100 countries. However, COVID-19 pneumonia with spontaneous pneumothorax is unknown. Case presentation: We reported a case of 66-year-old man infected with COVID-19, presenting with fever, cough and myalgia; The patient received supportive and empirical treatment including antiviral treatment, anti-inflammatory treatment, oxygen supply and inhalation therapy; The symptoms, CT images, laboratory results got improved after the treatments, and a throat swab was negative for COVID-19 PCR test; However, on the hospital day 30, the patient presented with a sudden chest pain and dyspnea. CT showed a 30–40% left-sided pneumothorax. Immediate thoracic closed drainage was performed and his dyspnea was rapidly improved. With five more times negative PCR tests for SARS-CoV-2 virus, the patient was discharged and home quarantine. Conclusion: This case highlights the importance for clinicians to pay attention to the appearance of spontaneous pneumothorax, especially patients with severe pulmonary damage for a long course, as well as the need for early image diagnose CT and effective treatment once pneumothorax occurs. Keywords: COVID-19, SARS-CoV-2 virus, Pneumonia, Pneumothorax

Background In late December 2019, an outbreak of the novel coronavirus (COVID-19) that was firstly reported in Wuhan, China, and was characterized as a pandemic by the WHO on March 11 [1, 2]. As of April 1, there were about 823, 626 confirmed cases and 40,598 deaths worldwide [3]. Nowadays, the methods for the definitive diagnosis and treatment of patients with mild symptoms have been well established [4], however clinical manifestations, management and prognosis of COVID-19 pneumonia with * Correspondence: [email protected] † Xiaoxing Chen and Guqin Zhang contributed equally to this work. 4 Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, 169 Eastlake Rd., Wuchang district, Wuhan 430071, Hubei province, China Full list of author information is available at the end of the article

complications such as pneumothorax may be much different. In this study, we report a case of COVID-19 pneumonia patient who developed spontaneous pneumothorax, which may provide further evidence for the suggestive management for such patients.

Case presentation The patient is a 66-year-old man living in Wuhan, who reported that he had an initial symptom of fever, dry cough and myalgia on January 18, without chills, dyspnea, chest pain, or diarrhea (Fig. 1). Two days later (January 20), he went to the clinic because of suspicious COVID-19 infection. The CT scan showed ground-glass opacities (GGO) in the basal segment of the right lower lobe (Fig. 2). Subsequently, a throat swab was obtained, and the pat