The correlation between plasma cytokine levels in jaundice-free children with biliary atresia
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The correlation between plasma cytokine levels in jaundice-free children with biliary atresia Zhi-Hong Jian, Li-Ching Wang, Chieh-Chung Lin, Jiaan-Der Wang Taiwan, China
Methods: There were 40 jaundice-free patients with BA and 28 normal controls enrolled. Patients were divided into 3 groups, including normal liver function, impaired liver function, and portal hypertension. Plasma concentration of Th1 [interferon-γ (INF-γ), interleukin (IL)-2], Th2 (IL-4, IL-10), Th3 [transforming growth factor-β1 (TGF-β1)], Th17 (IL-17) cytokines, and stromal cell-derived factor-1α (SDF-1α) were investigated. Results: The IFN-γ level was significantly higher in the BA patients with impaired liver function and portal hypertension than controls (P
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