The Essential Guide to Lithium Treatment
This book is a practical, up-to-date guide to the correct use of lithium for the short- and long-term treatment of mood disorders. Among the subjects addressed are the pharmacology and mechanisms of action of lithium, its use for maintenance treatment, th
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The Essential Guide to Lithium Treatment
Michael Bauer • Michael Gitlin
The Essential Guide to Lithium Treatment
Michael Bauer Technische Universtät Dresden University Hospital Carl Gustav Carus Dresden Germany
Michael Gitlin Geffen School of Medicine University of California Los Angeles Los Angeles, CA USA
ISBN 978-3-319-31212-5 ISBN 978-3-319-31214-9 DOI 10.1007/978-3-319-31214-9
(eBook)
Library of Congress Control Number: 2016936390 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
More than 65 years after its discovery for the treatment of mania, lithium continues as the most valuable treatment option for bipolar disorder. In the areas of both basic pharmacology and in clinical efficacy, much has been discovered about lithium since its introduction into modern psychiatry in 1949. Lithium is an intriguing medication for several reasons: it is a simple element easily found in the periodic table, yet it has demonstrated a unique, striking efficacy in preventing mood episodes in patients with bipolar and unipolar mood disorders. For example, during the past 25 years, lithium’s value as a suicide-preventing agent is increasingly acknowledged and has spurred new interest in its use. The ability of lithium to significantly reduce suicidal risk distinguishes it from the other mood-stabilizing agents currently available. Furthermore, basic research in the previous decade has demonstrated that lithium may possess neuroprotective properties in humans. These newer data suggest that lithium may even hold potential in preventing and treating dementia and other neurodegenerative diseases. This book is a practical, up-to-date guide to the optimal use of lithium for the short- and long-term treatment of mood disorders. It is intended primarily for use by clin
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