The importance of rheumatology biologic registries in Latin America
- PDF / 208,673 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 76 Downloads / 169 Views
REVIEW ARTICLE
The importance of rheumatology biologic registries in Latin America Maria de la Vega • Hellen M. da Silveira de Carvalho Lucio Ventura Rı´os • Maria V. Goycochea Robles • Gustavo C. Casado
•
Received: 6 July 2012 / Accepted: 8 December 2012 / Published online: 23 December 2012 Ó Springer-Verlag Berlin Heidelberg 2012
Abstract Rheumatoid arthritis is a systemic inflammatory disorder characterized by joint articular pain and disability. Although there is scarcity of data available on the incidence and prevalence of RA in Latin America, there is a growing recognition of this disease where chronic diseases are on the rise and infectious disease on the decline. RA is a substantial burden to patients, society, and the healthcare system. The heterogeneity identified within RA presents an opportunity for personalized medicine, especially in regions with such demographic diversity as that of Latin America. To understand the long-term effects of treatment for RA especially on safety, registries have been established, a number of which have been created in Latin America. Despite their weaknesses (e.g., lack of controls and randomization), registries have provided additional and complementary information on the use of biologics in
M. de la Vega (&) Sociedad Argentina de Reumatologı´a, Montes de Oca 587, 21°c, Buenos Aires, Argentina e-mail: [email protected] H. M. da Silveira de Carvalho Hospital de Base do Distrito Federal, Unidade de Reumatologia, Brası´lia, Brazil L. Ventura Rı´os Hospital General de Zona 194 IMSS, Hospital Central sur PEMEX, Me´xico City, Mexico M. V. Goycochea Robles HGR No. 1 IMSS, Colegio Mexicano de Reumatologı´a, Unidad de Investigacio´n, Me´xico City, Mexico G. C. Casado Sociedad Argentina de Reumatologı´a, Docente Autorizado de la Facultad de Medicina de la Universidad de Buenos Aires, Hospital Militar, Buenos Aires, Argentina
clinical practice in Latin America and other regions. Although certain challenges remain in the implementation and maintenance of registries, they continue to provide real-life data to clinical practice contributing to improved patient care. Keywords Rheumatoid arthritis Review Registries Latin America Biological therapy
Introduction Rheumatoid arthritis (RA) is a disorder characterized by joint and systemic inflammation, joint pain, deformity, and over the long-term, joint destruction [1]. Limited data are available on the incidence and prevalence of RA in Latin America. Community surveys using the Community Oriented Program for the Control of Rheumatic Diseases (COPCORD) approach have been conducted to determine the prevalence of RA in various countries in the region. In Argentina, a prevalence rate of 0.94 % was observed in a population surveyed in a city of Buenos Aires province [2]. In Cuba, a COPCORD study revealed a prevalence rate of 1.24 % [3] and, in Mexico, RA prevalence ranges from 0.3 to 2.8 % [4–7]. An estimated conservative prevalence rate of 0.4 % can be applied to Latin America as a whole, with a higher occurrence in female
Data Loading...
