The preliminary comparative results between Covid-19 and non-Covid-19 patients in Western China
- PDF / 480,367 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 70 Downloads / 151 Views
RESEARCH ARTICLE
Open Access
The preliminary comparative results between Covid-19 and non-Covid-19 patients in Western China Yanzi Li1†, Hongxia Li1†, Jianfeng Han2* and Lin Yang2,3*
Abstract Background: This study aims to investigate the comparative clinical characteristics of Covid-19 and non-Covid-19 patients. Methods: Fifteen Covid-19 and 93 non-Covid-19 patients were included in RNA testing. All epidemiological and clinical data were collected and analyzed, and then comparative results were carried out. Results: Covid-19 patients were older (46.40 ± 18.21 years vs 34.43 ± 18.80 years) and had a higher body weight (70.27 ± 10.67 kg vs 60.54 ± 12.33 kg, P < 0.05). The main symptoms that were similar between Covid-19 and nonCovid-19 patients, and Covid-19 patients showed a lower incidence of sputum production (6.67% vs 45.16%, P < 0.01) and a lower white-cell count (4.83 × 109/L vs 7.43 × 109/L) and lymphocyte count (0.90 × 109/L vs 1.57 × 109/L, P < 0.01). Although there were no differences, C-reactive protein and interleukin-6 were elevated in Covid-19 patients. The sensitivity and negative predictive value of CT images were 0.87 and 0.97, respectively. Covid-19 patients showed a higher contact history of Wuhan residents (80% vs 30.11%) and higher familial clustering (53.33% vs 8.60%, P < 0.001). Covid-19 patients showed a higher major adverse events (ARDS, 13.33%; death, 6.67%; P < 0.05). Conclusion: Our results suggested that Covid-19patients had a significant history of exposure and familial clustering and a higher rate of severe status; biochemical indicators showed lymphocyte depletion. Keywords: Coronavirus, Covid-19, Pneumonia, Epidemiology, Comparative results
Background Since the first 4 cases of coronavirus pneumonia were reported in late December 2019 in Wuhan, China, an outbreak of the 2019 coronavirus disease (Covid-19) has been reported in all areas of China and dozens of other countries [1, 2]; this new virus was identified as the seventh coronavirus using deep gene sequence analysis [3]. By February 27, 2020, 78,630 people were infected with new coronavirus pneumonia, of which 2747 died. Similar to severe acute respiratory syndrome coronavirus * Correspondence: [email protected]; [email protected] † Yanzi Li and Hongxia Li contributed equally to this work. 2 Department of Administrative Office, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China Full list of author information is available at the end of the article
(SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) with high mortality, Covid-19 is causing serious disease and global health concerns [4–6]. Although several reports have revealed the epidemiological and clinical characteristics of Covid-19 [1, 7], there are currently no reports on the clinical features of Covid-19 in Western China, and no literature on the clinical differences between Covid-19 and non-Covid-19 patients. Thus, analyzing the clinical characteristics of these two groups of patients will play an important role in the treatment of t
Data Loading...
