The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish

Zebrafish (Danio rerio) is rapidly becoming a popular model organism in neuroscience research. The rights and wrongs of zebrafish, written by top experts in the field, summarizes the principles of behavioral neurophenotyping using this model species, and

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The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish

The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish

Allan V. Kalueff Editor

The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish

Editor Allan V. Kalueff The International Zebrafish Neurosceince Research Consortium (ZNRC) and ZENEREI Research Center Slidell, LA, USA College of Food Science and Technology Research Institute of Marine Drugs and Nutrition Guangdong Ocean University Zhanjiang, Guangdong, China Institute of Translational Biomedicine St. Petersburg State University St. Petersburg, Russia Institutes of Chemical Technology and Natural Sciences Ural Federal University Ekaterinburg, Russia

ISBN 978-3-319-33773-9    ISBN 978-3-319-33774-6 (eBook) DOI 10.1007/978-3-319-33774-6 Library of Congress Control Number: 2016957392 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) has become a very popular model organism in biomedical research. But, as we are often asked, why zebrafish? This small aquatic vertebrate fish species has traveled all the way from its natural habitat in India to emerge as a promising model organism in developmental biology, genetics, physiology, and toxicology. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75 % based on coding regions), it is not surprising that humans and fish are very similar physi