Topical Therapy I: Corticosteroids and Vitamin D Analogues

Psoriasis is a common disease affecting approximately 2% of the population worldwide. Topical therapies play an integral role in the treatment of patients with mild-to-moderate disease. The mainstays of treatment are topical corticosteroids, vitamin D ana

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Advances in Psoriasis

Jeffrey M. Weinberg  •  Mark Lebwohl Editors

Advances in Psoriasis A Multisystemic Guide Second Edition

Editors Jeffrey M. Weinberg Department of Dermatology, Suite 11D Icahn School of Medicine at Mount Sinai New York, NY USA

Mark Lebwohl Icahn School of Medicine at Mount Sinai New York, NY USA

ISBN 978-3-030-54858-2    ISBN 978-3-030-54859-9 (eBook) https://doi.org/10.1007/978-3-030-54859-9 © Springer Nature Switzerland AG 2014, 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

1 Introduction to and History of Psoriasis and Psoriasis Therapy����������������������������������������������������������������������������   1 John B. Cameron and Abby S. Van Voorhees 2 Pathophysiology of Psoriasis/Novel Pathways������������������������������   9 Jeremy M. Hugh and Jeffrey M. Weinberg 3 Psoriasis: Clinical Review and Update������������������������������������������  19 Ivan Grozdev and Neil J. Korman 4 Psoriasis: Epidemiology, Potential Triggers, Disease Course����������������������������������������������������������������������������������  27 Ivan Grozdev and Neil J. Korman 5 Topical Therapy I: Corticosteroids and Vitamin D Analogues ����������������������������������������������������������������������  39 Eric J. Yang and Shari R. Lipner 6 Topical Therapy II: Retinoids, Immunomodulators, and Others����������������������������������������������������������������������������������������  51 Lyn C. Guenther 7 Topical Therapy II: Retinoids, Immunomuodulators, and Others/Ultraviolet Therapy for Psoriasis ������������������������������  71 Kristen M. Beck and John Koo 8 Laser Therapy in Psoriasis�������������������������������