Translational Pancreatic Cancer Research From Understanding of Mecha

This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to deve

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Christoph W. Michalski Jonas Rosendahl Patrick Michl Jörg Kleeff   Editors

Translational Pancreatic Cancer Research From Understanding of Mechanisms to Novel Clinical Trials

Molecular and Translational Medicine Series Editors William B. Coleman American Society for Investigative Pathology Rockville, MD, USA Gregory J. Tsongalis Department of Pathology and Laboratory Medicine Dartmouth-Hitchcock Medical Center Lebanon, NH, USA

As we enter into this new era of molecular medicine with an expanding body of knowledge related to the molecular pathogenesis of human disease and an increasing recognition of the practical implications for improved diagnostics and treatment, there is a need for new resources to inform basic scientists and clinical practitioners of the emerging concepts, useful applications, and continuing challenges related to molecular medicine and personalized treatment of complex human diseases. This series of resource/reference books entitled Molecular and Translational Medicine is primarily concerned with the molecular pathogenesis of major human diseases and disease processes, presented in the context of molecular pathology, with implications for translational molecular medicine and personalized patient care. More information about this series at http://www.springer.com/series/8176

Christoph W. Michalski  •  Jonas Rosendahl Patrick Michl  •  Jörg Kleeff Editors

Translational Pancreatic Cancer Research From Understanding of Mechanisms to Novel Clinical Trials

Editors Christoph W. Michalski Department of Visceral, Vascular and Endocrine Surgery University Hospital Halle (Saale) Halle (Saale) Sachsen-Anhalt Germany Patrick Michl Department of Internal Medicine I University Hospital Halle (Saale) Halle (Saale) Sachsen-Anhalt Germany

Jonas Rosendahl Department of Internal Medicine I University Hospital Halle (Saale) Halle (Saale) Sachsen-Anhalt Germany Jörg Kleeff Department of Visceral, Vascular and Endocrine Surgery University Hospital Halle (Saale) Halle (Saale) Sachsen-Anhalt Germany

ISSN 2197-7852     ISSN 2197-7860 (electronic) Molecular and Translational Medicine ISBN 978-3-030-49475-9    ISBN 978-3-030-49476-6 (eBook) https://doi.org/10.1007/978-3-030-49476-6 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume t