Uterine Endometrial Function
This book focuses on uterine endometrial function and receptivity from multiple perspectives. The chapters cover a variety of topics including the role of estrogen and progesterone, animal models, parameters for assessing endometrial receptivity, the mech
- PDF / 3,919,636 Bytes
- 156 Pages / 439.42 x 683.15 pts Page_size
- 57 Downloads / 151 Views
123
Uterine Endometrial Function
ThiS is a FM Blank Page
Hideharu Kanzaki Editor
Uterine Endometrial Function
Editor Hideharu Kanzaki Department of Obstetrics and Gynecology Kansai Medical University Osaka, Japan
ISBN 978-4-431-55970-2 ISBN 978-4-431-55972-6 DOI 10.1007/978-4-431-55972-6
(eBook)
Library of Congress Control Number: 2016938798 © Springer Japan 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Japan KK
Preface
This book focuses, from multiple perspectives, on uterine endometrial function and its receptivity for the fertilized ovum. Morphological and functional uterine endometrial changes are primarily controlled by ovarian steroidal hormones and are regulated by many secondary messenger molecules. Despite nearly 40 years of experience with in vitro fertilization (IVF), the rate of successful implantations remains low. Steady progress has been made in understanding of the fertilization process, and the development of the intracytoplasmic sperm injection technique has remarkably improved the fertilization rate in vitro. As well, advances in culture medium and equipment enable the fertilized ovum to develop up to the pre-implantation blastocyst stage. On the other hand, because of the limitations of experimental models, our understanding of the implantation process is still greatly limited, but recent molecular and genetic studies have gradually been clarifying the details. Endometrial receptivity results from an orchestrated interplay between the fertilized ovum and the maternal uterine endometrium; and its receptive status, known as the window of implantation, is reached only briefly in the mid-luteal phase as a result of a harmonized reciprocal relationship. Abnormal endometrial receptivity is, therefore, one of the factors contributing to reduced reproductive potential in women and is the greatest challenge in infertility treatm
Data Loading...
