Yeast Stress Responses
Every cell has developed mechanisms to respond to changes in its environment and to adapt its growth and metabolism to unfavorable conditions. The unicellular eukaryote yeast has long proven as a particularly useful model system for the analysis of cellul
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Springer Berlin Heidelberg NewYork Hong Kong London Milan Paris Tokyo
Stefan Hohmann Willem H. Mager
(Editors)
Yeast Stress Responses With 61 Figures and 12 Tables
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Professor Dr. Stefan Hohmann Department of Cell and Molecular Biology/Microbiology G¨oteborg University Box 462, 405 30 G¨oteborg, Sweden Dr.Willem H. Mager Department of Biochemistry & Molecular Biology Division of Scheikunde, Vrije Universiteit De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands
ISSN 1610-2096 ISBN 3-540-43926-9 Springer-Verlag Berlin Heidelberg New York Cataloging-in-Publication Data applied for Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the Internet at . This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under German Copyright Law. Springer-Verlag Berlin Heidelberg New York a member of BertelsmannSpringer Science+Business Media GmbH http://www.springer.de © Springer-Verlag Berlin Heidelberg 2003 Printed in Germany The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover-Design: design & production GmbH, Heidelberg Typesetting: Camera-ready by editors Data-conversion: PTP-Berlin, Stefan Sossna e.K. Printing: Saladruck, Berlin Bookbinding: St¨urtz AG, W¨urzburg Printed on acid-free paper SPIN 10849325 39/3150 ih - 5 4 3 2 1 0
Table of Contents
Introduction ............................................................................................................. 1 Stefan Hohmann and Willem H. Mager.............................................................. 1 What is stress? ............................................................................................ 1 Studies of stress responses ......................................................................... 2 Cell proliferation and stress ....................................................................... 3 Aim of the stress response.......................................................................... 4 Phases of the stress response...................................................................... 5 Sensing and signalling................................................................................ 6 Adaptation to stress ..........................................................
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