Stress Responses Methods and Protocols
This volume focuses on detecting different cellular stresses, measuring pathological consequences within the cell, and investigating the role of cellular stresses in select diseases. In addition, this book reviews the crosstalk between different stre
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Christine M. Oslowski Editor
Stress Responses Methods and Protocols
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Stress Responses Methods and Protocols
Edited by
Christine M. Oslowski Wentworth Institute of Technology, Boston, MA, USA
Editor Christine M. Oslowski Wentworth Institute of Technology Boston, MA, USA
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-2521-6 ISBN 978-1-4939-2522-3 (eBook) DOI 10.1007/978-1-4939-2522-3 Library of Congress Control Number: 2015934151 Springer New York Heidelberg Dordrecht London © Springer Science+Business Media New York 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Humana Press is a brand of Springer Springer Science+Business Media LLC New York is part of Springer Science+Business Media (www.springer.com)
Preface Cells are bombarded by stresses on a regular basis. Luckily, cells are armed with several mechanisms to mitigate cell stress and promote cell survival. However, under severe stress conditions, cells undergo dysfunction and ultimately death. This volume of Methods in Molecular Biology includes an array of protocols to detect and study the different cellular stresses, measure their pathological consequences within the cell, and investigate the role of cellular stresses in select diseases. Understanding the mechanisms of the multiple cellular pathways and outcomes triggered by such stresses will lead to the development of novel therapeutics to prevent or treat disease. At the conclusion of this volume, reviews on the crosstalk between different pathways, stress responses during ageing, and targeting stress are included. Boston, MA, USA
Christine M. Oslowski
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Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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