2008 Annual Meeting Student Poster Abstracts
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2008 Annual Meeting Student Poster Abstracts The accepted Student Poster Abstracts are printed Mow. The posters prosent scientific devdopments related to topics addressed in meeting tut0nals and sessions, and were displayed outside the entmnce to Exhibit Hall A on the Exhibit Hall Level of the Boston Convention and Exhibition Center at the 44th DlA Annual Meeting. The Student Poster Session took place
on Mondq, June23. The chairpersons for the Student Poster Session were Fmnqoise G. Pmdd, PhD, and Fmncis B. Palumbo, PhD, ID, bothfrom the University of Maryland Schd of Pharmaq, and Stephen A. Sonstein, PhD, MS, f.wn Eastern Michigan University.
Severe cutaneous adverse drug reactions associated with use of carbamazepine:the role of systematic review in pharmacovigilance Ashish Triveni Prasad Shukla SVKM's NMlMS University, India
Method Eight institutions participated representing many regions of the United States, including large teaching pediatric hospitals and smaller hospital. The 17-item questionnaire targets the use of SSRIs and mixed mechanism agents used to treat depressive and/or anxiety disorders.
Objective This research work is to test the application of systematic review methods as new approach to the field of pharmacovigilance of drugs.
Results Sixty-eight percent of pediatric oncologists reported prescribing an antidepressant to children with cancer. Of those, 54% claim the FDA black label warning has not affected their prescribing practice.
Method A MEDLINE database and Canadian Adverse Drug Reactions Monitoring Programme (CADRMP) database (reference database) search tracking for cases of carbamazepine-induced severe cutaneous adverse drug reactions was carried out. All the case studies reporting causal relationship were included.
Conclusion Interdisciplinary work with psychology and psychiatry may be helpful to the oncologists in treating depression in these children. It is also of importance to evaluate the benefits of nonpharmacologic treatment such as behavioral cognitive therapies in this special population.
Results In all 40 cases and 36 cases were tracked from MEDLINE database and CADRMP database respectively. The mean age, dose, and time to onset for cases reported with SJS,SJSflEN overlap, and TEN was found to be 40,325 mg, 14 days in published cases and 38,222 mg and 26 days in CADRMP cases. Conclusion The study indicates the reactions occur in therapeutic dose and most likely within 2-3 weeks of therapy with CBZ. This study can serve the industry and regulatory decision makers, by demonstrating another approach to enhancing pharmacovigilance of new drugs postmarketing.
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Factors that influence the decision to participate in clinical research trials: a pilot study and model for clinical researchers Kristin Stonebraker Gillenwater Kansas City University of Medicine and Biosciences Objective By employing a novel approach to investigate factors that influence participation in a clinical research trial, we eliminated many of the limitations of previous research and describe
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