2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS

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2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS JianQiao Zhou1 LiXue Yin2 Xi Wei3 Sheng Zhang3 YanYan Song4 BaoMing Luo5 JianChu Li6 LinXue Qian7 LiGang Cui8 Wen Chen8 ChaoYang Wen9 YuLan Peng10 Qin Chen11 Man Lu12 Min Chen13,14 Rong Wu15 Wei Zhou1 EnSheng Xue16 YingJia Li17 LiChun Yang18 ChengRong Mi19 RuiFang Zhang20 Gang Wu21 GuoQing Du22 DaoZhong Huang23 WeiWei Zhan1 The Superficial Organ and Vascular Ultrasound Group of the Society of Ultrasound in Medicine of the Chinese Medical Association The Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound ●





















































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Received: 4 February 2020 / Accepted: 28 July 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract Thyroid nodules are very common all over the world, and China is no exception. Ultrasound plays an important role in determining the risk stratification of thyroid nodules, which is critical for clinical management of thyroid nodules. For the past few years, many versions of TIRADS (Thyroid Imaging Reporting and Data System) have been put forward by several institutions with the aim to identify whether nodules require fine-needle biopsy or ultrasound follow-up. However, no version of TIRADS has been widely adopted worldwide till date. In China, as many as ten versions of TIRADS have been used in different hospitals nationwide, causing a lot of confusion. With the support of the Superficial Organ and Vascular Ultrasound Group of the Society of Ultrasound in Medicine of the Chinese Medical Association, the Chinese-TIRADS that is in line with China’s national conditions and medical status was established based on literature review, expert consensus, and multicenter data provided by the Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound. Keywords Thyroid nodule Diagnostic imaging Ultrasonography Risk assessment Biopsy Fine needle ●



Introduction As a highly prevalent disease, thyroid nodules can be detected by ultrasound among 19–68% of the general population, and majority of these were benign nodules without any clinical significance [1, 2]. The prevalence of thyroid nodules detected by ultrasound in China is about

Members of The Superficial Organ and Vascular Ultrasound Group of the Society of Ultrasound in Medicine of the Chinese Medical Association and The Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound are listed below Acknowledgements. * JianQiao Zhou [email protected] * LiXue Yin [email protected] * WeiWei Zhan [email protected] Extended author information available on the last page of the article







20–35% [3–6]. Of all the patients with thyroid nodules, 7–15% are malignant based on their age, gender, radiation history, family history, and other factors [2]. Ultrasound is the best imaging method for thyroid, and plays an important role in the diagnosis and man