A neonatal cluster of novel coronavirus disease 2019: clinical management and considerations
- PDF / 611,706 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 18 Downloads / 146 Views
RESEARCH
Open Access
A neonatal cluster of novel coronavirus disease 2019: clinical management and considerations Nicole Olivini1* , Francesca Ippolita Calò Carducci2, Veronica Santilli2, Maria Antonietta De Ioris1, Alessia Scarselli1, Dario Alario3, Caterina Geremia1, Mary Haywood Lombardi1, Caterina Marabotto1, Rosanna Mariani1, Raffaele Edo Papa1, Emanuela Peschiaroli1, Raffaella Scrocca1, Serena Sinibaldi1, Andrea Smarrazzo1, Pietro Stella1, Stefania Bernardi2, Sara Chiurchiù4, Paola Pansa4, Lorenza Romani4, Carletti Michaela5, Carlo Concato6, Domenico Umberto De Rose7, Gugliemo Salvatori7, Paolo Rossi2,8, Alberto Villani4, Andrea Dotta7, Patrizia D’Argenio2 and Andrea Campana1
Abstract Background: Lately, one of the major clinical and public health issues has been represented by Coronavirus disease of 2019 (COVID-19) during pregnancy and the risk of transmission of the infection from mother to child. Debate on perinatal management and postnatal care is still ongoing, principally questioning the option of the joint management of mother and child after birth and the safety of breastfeeding. According to the available reports, neonatal COVID-19 appears to have a horizontal transmission and seems to be paucisymptomatic or asymptomatic, compared to older age groups. The aim of this work is to describe a cluster of neonatal COVID-19 and discuss our experience, with reference to current evidence on postnatal care and perinatal management. Methods: This is a retrospective observational case series of five mother-child dyads, who attended the Labor and Delivery Unit of a first-level hospital in Italy, in March 2020. Descriptive statistics for continuous variables consisted of number of observations, mean and the range of the minimum and maximum values. Results: Five women and four neonates tested positive for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In one case, the mother-child dyad was separated and the neonate remained negative on two consecutive tests. Two positive neonates developed symptoms, with a predominant involvement of the gastrointestinal tract. Blood tests were unremarkable, except for a single patient who developed mild neutropenia. No complications occurred. (Continued on next page)
* Correspondence: [email protected] 1 Pediatrics Unit, University Department of Pediatrics (DPUO), Bambino Gesù Children’s Hospital – IRCCS, Via della Torre di Palidoro, 00050 Fiumicino, Rome, Italy Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit l
Data Loading...
