Advances in Membrane Proteins Building, Signaling and Malfunction
This book reviews recent advances regarding the biochemical and biophysical properties of membrane proteins and their applications in biomedicine. Divided into two thematic parts, this second volume addresses proteins’ formation, signaling and malfunction
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Advances in Membrane Proteins Building, Signaling and Malfunction
Advances in Membrane Proteins
Yu Cao Editor
Advances in Membrane Proteins Building, Signaling and Malfunction
Editor Yu Cao Department of Orthopaedics and Institute of Precision Medicine, Shanghai Key Laboratory of Orthopaedic Implant Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China
ISBN 978-981-13-9076-0 ISBN 978-981-13-9077-7 (eBook) https://doi.org/10.1007/978-981-13-9077-7 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Acknowledgement
This book is supported by the National Key Research and Development Program of China (2017YFC1001303 and 2018YFC1004704), NSFC-CAS Joint Fund for Research Based on Large-Scale Scientific Facilities (U1632132), and SHIPM-pi fund No. JY201804 from Shanghai Institute of Precision Medicine, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine.
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Contents
Lipid Homeostasis on Cell Membrane���������������������������������������������������������� 1 Xian-Cheng Jiang A Historical Perspective of G Protein-Coupled Receptor Structural Biology �������������������������������������������������������������������������� 31 Yang Chen, Ying Xia, and Yu Cao Membrane Proteins as Targets for Biological Drugs������������������������������������ 49 Vanita D. Sood and Alec W. Gross Cell Adhesion Molecules���������������������������������������������������������������������������������� 67 Xiajing Tong and Yan Zou The Biosynthesis and Folding of Oily Peptide Chains���������������������������������� 85 Kai Li and Shi-Qing Cai Mechanism of Qual
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