Age over 65 years and high levels of C-reactive protein are associated with the risk of preoperative deep vein thrombosi
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(2020) 15:559
RESEARCH ARTICLE
Open Access
Age over 65 years and high levels of Creactive protein are associated with the risk of preoperative deep vein thrombosis following closed distal femur fractures: a prospective cohort study Junzhe Zhang1,2†, Kuo Zhao1,2†, Junyong Li1,2,3†, Hongyu Meng1,2, Yanbin Zhu1,2 and Yingze Zhang1,2*
Abstract Background: In this study, we investigated the epidemiological characteristics and predictors of preoperative newonset deep vein thrombosis (DVT) in adult patients with closed distal femur fractures (DFFs). Methods: The study was designed as a prospective cohort trial at the Third Hospital of Hebei Medical University. From October 2018 to June 2020, a total of 160 patients with closed DFFs were enrolled to assess the location and prognosis of preoperative DVT. The patients were followed up for 2 months. Duplex ultrasonography (DUS) was used to diagnose patients with DVT. The patients were divided into two groups (DVT group and non-DVT group). The DVT was then classified into proximal, distal, and mixed thromboses. The Mann-Whitney U test or t test, receiver operating characteristic (ROC) analyses, univariate Chi-square analyses, and multiple logistic regression analyses were used to analyze the adjusted predictors of DVT. (Continued on next page)
* Correspondence: [email protected] † Junzhe Zhang, Kuo Zhao and Junyong Li contributed equally to this work. 1 Department of Orthopaedic Surgery, the Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang 050051, Hebei Province, People’s Republic of China 2 Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Research Institution of Hebei Province, Shijiazhuang, Hebei Province, People’s Republic of China Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Zhang et al. Journal of Orthopaedic Surgery and Research
(2020) 15:559
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Results: The overall incidence of preoperati
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