Alternatives to Animal Testing Proceedings of Asian Congress 2016
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more
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ernatives to Animal Testing Proceedings of Asian Congress 2016
Alternatives to Animal Testing
Hajime Kojima Troy Seidle Horst Spielmann •
Editors
Alternatives to Animal Testing Proceedings of Asian Congress 2016
Editors Hajime Kojima National Institute of Health Sciences Kawasaki, Kanagawa, Japan
Troy Seidle Humane Society International Montreal, QC, Canada
Horst Spielmann Institut für Pharmazie Free University of Berlin Berlin, Germany
ISBN 978-981-13-2446-8 ISBN 978-981-13-2447-5 https://doi.org/10.1007/978-981-13-2447-5
(eBook)
Library of Congress Control Number: 2018964686 © The Editor(s) (if applicable) and The Author(s) 2019 This book is an open access publication. Open Access This book is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence and indicate if changes were made. The images or other third party material in this book are included in the book’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the book’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Contents
Zebrafish, Danio Rerio as a Replacement Alternative Model Useful in CKDu Experiments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mangala Gunatilake
1
Testing Method Development and Validation for in Vitro Skin Irritation Testing (SIT) by Using Reconstructed Human Epidermis (RhE) Skin Equivalent - EPiTRI® . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Yu-Chun Lin, Hui-Chun Hsu, Chiu-Hsing Lin, Cheng-Yi Wu, Wannhsin Chen, and Huey-Min Lai
8
Development the Technique for the Preparation and Characterization of Reconstructed Human Epidermis (RHE) . . . . . . . . . . . . . . . . . . . . . . Herlina B. Setijanti, Eka Rusmawati, Rahmi Fitria, Tuty Erlina, Rina Adriany, and Murtiningsih Alternative Research (3Rs) in the World, Asia and Japan . . . . . . . . . . . Tsutomu Miki Kurosawa
20
33
Approaches to Reducing Animal Use for Acute Toxicity Testing: Retrospective Analyses of Pesticide Data . . . . . . . . . . . . . . . . . . . . . . . . Judy Strickland, Michael W. Paris, David Allen, and Warren Casey
37
Progress in Eliminating One-Year Dog Studies for the Safety Assessment of Pesticides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Horst Spielmann
50
Cosmetic Regulation and Alternatives to Animal Experimentation in India . . . . . . . . . . . . . . . . . .
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